Serum Thymus and Activation-Regulated Chemokine Level Monitoring May Predict Disease Relapse Detected by PET Scan after Reduced-Intensity Allogeneic Stem.

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Presentation transcript:

Serum Thymus and Activation-Regulated Chemokine Level Monitoring May Predict Disease Relapse Detected by PET Scan after Reduced-Intensity Allogeneic Stem Cell Transplantation in Patients with Hodgkin Lymphoma Lucia Farina, Francesca Rezzonico, Francesco Spina, Anna Dodero, Arabella Mazzocchi, Flavio Crippa, Alessandra Alessi, Serena Dalto, Simonetta Viviani, Paolo Corradini Biology of Blood and Marrow Transplantation Volume 20, Issue 12, Pages 1982-1988 (December 2014) DOI: 10.1016/j.bbmt.2014.08.016 Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 TARC values in PET-positive and PET-negative patients and in patients who relapsed after alloSCT. The line indicates the cut-off value of 1726 ng/mL. Biology of Blood and Marrow Transplantation 2014 20, 1982-1988DOI: (10.1016/j.bbmt.2014.08.016) Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 PFS of the patients who had at least 1 value of TARC > 1726 ng/mL within the first year after alloSCT (dotted line) and those who had always TARC < 1726 ng/mL during the first year after alloSCT (continuous line) (P = .031). Biology of Blood and Marrow Transplantation 2014 20, 1982-1988DOI: (10.1016/j.bbmt.2014.08.016) Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 3 TARC monitoring in patients who relapsed after allogeneic stem cell transplantation. CSA indicates cyclosporine; VGPR, very good partial remission; PR, partial remission; benda, bendamustine; chemo, chemotherapy. Biology of Blood and Marrow Transplantation 2014 20, 1982-1988DOI: (10.1016/j.bbmt.2014.08.016) Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 4 Potential use of TARC monitoring in patients with Hodgkin lymphoma after allogeneic stem cell transplantation. Biology of Blood and Marrow Transplantation 2014 20, 1982-1988DOI: (10.1016/j.bbmt.2014.08.016) Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions