Primary Malignant Pericardial Mesothelioma Mimicking Pericardial Metastasis from Adenocarcinoma Masafumi Horie, MD, Satoshi Noguchi, MD, Wakae Tanaka,

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Primary Malignant Pericardial Mesothelioma Mimicking Pericardial Metastasis from Adenocarcinoma Masafumi Horie, MD, Satoshi Noguchi, MD, Wakae Tanaka, MD, Hisanao Yoshihara, MD, PhD, Masaki Kawakami, MD, PhD, Masaru Suzuki, MD, Yoshio Sakamoto, MD, PhD, Teruaki Oka, MD, PhD Journal of Thoracic Oncology Volume 5, Issue 12, Pages 2012-2014 (December 2010) DOI: 10.1097/JTO.0b013e3181f624da Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 F-18 fluorodeoxyglucose positron emission tomography scan showing aggregations around the ascending aorta, pulmonary artery, and the pericardium. Journal of Thoracic Oncology 2010 5, 2012-2014DOI: (10.1097/JTO.0b013e3181f624da) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 a, Gross pathologic specimen showing that the heart was entirely encased with a yellowish tumor occupying the pericardial space. b, Histologic analysis revealed atypical proliferation of epithelioid cells forming large and small glandular ducts (hematoxylin and eosin stain; original magnification, ×100). c, Histologic analysis revealed atypical and irregular proliferation of spindle cells (hematoxylin and eosin stain; original magnification, ×100). d, Immunohistochemical staining for calretinin was positive in the nuclei and cytoplasm of the epithelioid and sarcomatous tumor cells (original magnification, ×100). Journal of Thoracic Oncology 2010 5, 2012-2014DOI: (10.1097/JTO.0b013e3181f624da) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions