Patterns of p53 mutations according to smoking habits in a) all lung cancers minus nonsmokers (n = 1,289), b) smokers with lung cancer (n = 419), c) nonsmokers.

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Patterns of p53 mutations according to smoking habits in a) all lung cancers minus nonsmokers (n = 1,289), b) smokers with lung cancer (n = 419), c) nonsmokers with lung cancer (153), and d) brain, breast and colorectal cancer (n = 4,516). ▪: A:T>C:G; : A:T... Patterns of p53 mutations according to smoking habits in a) all lung cancers minus nonsmokers (n = 1,289), b) smokers with lung cancer (n = 419), c) nonsmokers with lung cancer (153), and d) brain, breast and colorectal cancer (n = 4,516). ▪: A:T>C:G; : A:T>G:C; ▒: A:T>T:A; ░: G:C>A:T; : G:C>A:T at CpG; ▓: G:C>C:G; : G:C>T:A; □: deletion/insertion/complex. Reproduced from [5] with permission from the publisher. P. Vineis Eur Respir Rev 2008;17:182-186 ©2008 by European Respiratory Society