Genotyping Results Each person was typed for 3 unlinked Short Tandem Repeat loci (STR) vWFII – chromosome 12, intron 40 of the vWF gene UT 2203 – chromosome.

Slides:

Advertisements

Similar presentations

A quantitative trait locus not associated with cognitive ability in children: a failure to replicate Hill, L. et al.

Advertisements

For each characteristic you have two alleles; one from your biological mother and one from your biological father. A particular chromosome from your biological.

Two-locus systems. Scheme of genotypes genotype Two-locus genotypes Multilocus genotypes genotype.

Forensic DNA Analysis (Part II)

Gene Linkage and Genetic Mapping

Linkage and Gene Mapping. Mendel’s Laws: Chromosomes Locus = physical location of a gene on a chromosome Homologous pairs of chromosomes often contain.

Chapter 3: The Modern Synthesis. Hardy-Weinberg equilibrium If no selection and mating is random (i.e., no processes acting to change the distribution.

1) Linkage means A) Alleles at different loci are independent B) Alleles at different loci are physically close to each other and on the same chromosome.

DNA Fingerprinting and Forensic Analysis

Our Test Organism Drosophila simulans. Trait of Interest Red vs. White.

 How does the graph represent a gel? Each group filled in a ‘band’ that represents where different – sized DNA fragments would have migrated on a gel,

Genotyping Results Each person was typed for 3 unlinked Short Tandem Repeat loci (STR) vWFII – chromosome 12, intron 40 of the vWF gene UT 2203 – chromosome.

Chapter 17: Evolution of Populations

Paternity Testing Biology Alliance May 13. A pair of homologous chromosomes, (one from mom, one from dad) Gene unit of DNA information about a trait.

DNA Forensics. DNA Fingerprinting - What is It? Use of molecular genetic methods that determine the exact genotype of a DNA sample in a such a way that.

Genetic Mapping Oregon Wolfe Barley Map (Szucs et al., The Plant Genome 2, )

Overview: Genetic Mapping Basic Principles Genetic Mapping in Experimental Organisms Genetic Mapping in Humans Genes, RFLPs, SNPs Meiosis, Independent.

Genetic Mapping (Chapt. 5)

Human Identity Testing Purpose: Match a person to a DNA sample. Examples: Paternity Test Genetic History Historical (Thomas Jefferson, Sally Hemings) Genealogical.

Short Tandem Repeats (STR) and Variable Number Tandem Repeats (VNTR)

Quantitative Genetics

Alu Polymorphysims as Identity Markers Using PCR and Gel Electrophoresis.

Genes Traffic lights quiz Hold up the coloured card that matches the correct answer you see on the screen.

1 DNA Polymorphisms: DNA markers a useful tool in biotechnology Any section of DNA that varies among individuals in a population, “many forms”. Examples.

Heredity  The study of the passing on of traits from parents to kids.  Learn how and why physical and behavioral characteristics are passed on to from.

In The Name of GOD Genetic Polymorphism M.Dianatpour MLD,PHD.

Simple-Sequence Length Polymorphisms SSLPs Short tandemly repeated DNA sequences that are present in variable copy numbers at a given locus. Scattered.

PCR Y.Martinez, LSHS, 2014 DIRECTIONS: COPY NOTES IN ORANGE.

Chapter 23: Evaluation of the Strength of Forensic DNA Profiling Results.

Types of genome maps Physical – based on bp Genetic/ linkage – based on recombination from Thomas Hunt Morgan's 1916 ''A Critique of the Theory of Evolution'',

All rights Reserved Cengage/NGL/South-Western © 2016.

Let’s see what you know! 23,000, microscope, nucleus, chromosomes, divide, DNA, proteins, code, genes __________.

Genetics Genetic material is found in the nucleus of living cells.

 Mitosis 1875  Meiosis 1890s  Chromosomes being the “inheritance factors” that Mendel referred to 1902.

Restriction Fragment Length Polymorphism. Definition The variation in the length of DNA fragments produced by a restriction endonuclease that cuts at.

Genes Observable traits are the result of genes. – Genes are found on the chromosomes in our cells – Each observable trait is determined by two genes,

Three generations of DNA testing

Simple-Sequence Length Polymorphisms

Genes within Populations

All rights Reserved Cengage/NGL/South-Western © 2016.

Dihybrid cross Used when looking at inheritance patterns of 2 genes on different chromosomes Independent assortment will separate the 2 homologous chromosomes.

All rights Reserved Cengage/NGL/South-Western © 2016.

Recombination (Crossing Over)

THE HUMAN GENOME Molecular Genetics.

Gene Linkage and Genetic Mapping

Evolution of populations

Gene Linkage and Genetic Mapping

Evolution of populations

JS 115 Validation Pre class activities Database issues- Continued

Emergence of Modern Science

Heredity Vocabulary Sexual Reproduction- a cell containing genetic info from the mother and a cell containing genetic info from the father combine into.

DNA Polymorphisms: DNA markers a useful tool in biotechnology

HARDY-WEINBERG and GENETIC EQUILIBRIUM

Genetic Map of Drosophila

Phenotype frequency: 30% blue eyes (or 0.3) 70% brown eyes (or 0.7)

DNA Identification: Biology and Information

DNA Identification: Biology and Information

Genes and Variations 16:1.

Study on the genetic polymorphisms of Y chromosomal DNA short tandem repeat loci applied to analyzing the relative affinities among ethnic groups in Taiwan

Multiple Alleles An individual has two copies of each gene, so can only have two alleles of any gene, but there can be more than two alleles of a gene.

Lesson Overview 17.1 Genes and Variation.

DNA Analysis “The capacity to blunder slightly is the

DNA Profiling Vocabulary

Fertilization Notes Egg parent cell _ _

Phenotype frequency: 30% blue eyes (or 0.3) 70% brown eyes (or 0.7)

DNA Identification: Biology and Information

Messages through Bottlenecks: On the Combined Use of Slow and Fast Evolving Polymorphic Markers on the Human Y Chromosome Peter de Knijff The American.

Starter An animal has a diploid chromosome number of 14. Calculate the number of possible genotypes of gametes it produces due to independent segregation.

Presentation transcript:

Genotyping Results Each person was typed for 3 unlinked Short Tandem Repeat loci (STR) vWFII – chromosome 12, intron 40 of the vWF gene UT 2203 – chromosome 4, 60.16 cM UT 1376 – chromosome 4, 132.05 cM Individual genotyping results are in the MED2014_Genotypes.pdf file

Example – 3 STR Markers 162 166 202/202 285 289 vWF11 in red 162 166 202/202 285 289 vWF11 in red UT 2203 in blue UT 1376 in blue

Allele Frequencies

Genotype Summary and Sharing 125 Participants, 3 STRs vWF11 UT2203 UT1376 # of Students Unique Combinations 63 Pairs 18 154/162 199/199 289/289 3 162/162 202/202 162/170 199/202 162/172 166/166 285/289 162/166 4 9 No call for 1 or more loci 10

Population Tree

Population Tree (Europe only)