Volume 90, Pages (January 2019)

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Volume 90, Pages 70-71 (January 2019) Unusual Clinical Course and Imaging of D-Bifunctional Protein Deficiency, a Rare Leukodystrophy Amy Farkas, MD, Ruba Al-Ramadhani, MD, Kimberly McDonald, MD, Meredith Jordan, BA, David Joyner, MD Pediatric Neurology Volume 90, Pages 70-71 (January 2019) DOI: 10.1016/j.pediatrneurol.2018.09.001 Copyright © 2019 Terms and Conditions

FIGURE Diffusion-weighted imaging (DWI) of the initial MRI of the brain (A) demonstrates restricted diffusion of the parietal white matter including the subcortical U fibers. Initial FLAIR image (B) demonstrates extensive hyperintense signal in the biparietal white matter. DWI at five-month follow-up (C) demonstrates resolution of initial areas of restricted diffusion, but new involvement of the deep gray matter. FLAIR image at five-month follow-up (D) demonstrates extensive progression of the signal abnormality, now with involvement of the frontal white matter. Pediatric Neurology 2019 90, 70-71DOI: (10.1016/j.pediatrneurol.2018.09.001) Copyright © 2019 Terms and Conditions