Painful Ophthalmoplegia (Tolosa-Hunt Variant): Autopsy Findings in a Patient With Necrotizing Intracavernous Carotid Vasculitis and Inflammatory Disease.

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Presentation transcript:

Painful Ophthalmoplegia (Tolosa-Hunt Variant): Autopsy Findings in a Patient With Necrotizing Intracavernous Carotid Vasculitis and Inflammatory Disease of the Orbit  R. JEAN CAMPBELL, M.B., Ch.B.  Mayo Clinic Proceedings  Volume 62, Issue 6, Pages 520-526 (June 1987) DOI: 10.1016/S0025-6196(12)65478-0 Copyright © 1987 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 1 Base of skull, showing hemorrhagic discoloration of roof of right orbit. Mayo Clinic Proceedings 1987 62, 520-526DOI: (10.1016/S0025-6196(12)65478-0) Copyright © 1987 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 2 Specimen obtained from en bloc dissection of dorsum sellae together with pituitary and cavernous sinus. Note distended cavernous sinus on right and intramural thrombus within carotid artery. Mayo Clinic Proceedings 1987 62, 520-526DOI: (10.1016/S0025-6196(12)65478-0) Copyright © 1987 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 3 Photomicrographs of specimen shown in Figure 2. A, Wall of cavernous sinus shows mural clot (at left) and inflammatory tissue within adjacent bone (at right). (Hematoxylin and eosin; x40.) B, Granulation tissue in wall of right cavernous sinus. Mononuclear cells, new vessels, and fibroblasts are interspersed. (Hematoxylin and eosin; x400.) Mayo Clinic Proceedings 1987 62, 520-526DOI: (10.1016/S0025-6196(12)65478-0) Copyright © 1987 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 4 Postmortem angiogram, showing rupture of intracranial portion of right internal carotid artery. Mayo Clinic Proceedings 1987 62, 520-526DOI: (10.1016/S0025-6196(12)65478-0) Copyright © 1987 Mayo Foundation for Medical Education and Research Terms and Conditions