Effect of flare reaction to intra-articular injection on cartilage lubricating ability of human synovial fluid T.E. Ludwig, J.R. McAllister, V.M. Lun,

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Effect of flare reaction to intra-articular injection on cartilage lubricating ability of human synovial fluid T.E. Ludwig, J.R. McAllister, V.M. Lun, J.P. Wiley, T.A. Schmidt Osteoarthritis and Cartilage Volume 21, Pages S299-S300 (April 2013) DOI: 10.1016/j.joca.2013.02.625 Copyright © 2013 Terms and Conditions

Figure 1 [PRG4] in flare-SF after IA HA or corticosteroid injection. [PRG4] ±SEM in normal (NL) SF (N=29) shown by black lines. Samples selected for friction testing (HA flare only) are circled. Osteoarthritis and Cartilage 2013 21, S299-S300DOI: (10.1016/j.joca.2013.02.625) Copyright © 2013 Terms and Conditions

Figure 2 HAMW distribution in N=4 PRG4-deficient flare-SF samples selected for friction testing and N=14 normal (NL) SF (#= p<0.05) Osteoarthritis and Cartilage 2013 21, S299-S300DOI: (10.1016/j.joca.2013.02.625) Copyright © 2013 Terms and Conditions

Figure 3 Kinetic friction coefficient (<μkinetic,Neq>) at Tps=1.2 s of PRG4 deficient flare-SF with 450 μg/mL PRG4 and 1.0 mg/mL 1.5 MDa HA supplementation, and NLSF. Osteoarthritis and Cartilage 2013 21, S299-S300DOI: (10.1016/j.joca.2013.02.625) Copyright © 2013 Terms and Conditions