Michael J. Levy, William Ledger, Efstratios M. Kolibianakis, Pieta C

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Presentation transcript:

Is it possible to reduce the incidence of weekend oocyte retrievals in GnRH antagonist protocols? Michael J. Levy, William Ledger, Efstratios M. Kolibianakis, Pieta C. IJzerman-Boon, Keith Gordon Reproductive BioMedicine Online Volume 26, Issue 1, Pages 50-58 (January 2013) DOI: 10.1016/j.rbmo.2012.09.014 Copyright © 2012 Reproductive Healthcare Ltd. Terms and Conditions

Figure 1 Study design (recombinant FSH treatment arm of the Engage trial). The recombinant FSH dose could be reduced from day 6 onwards when required in the opinion of the investigator. HCG=human chorionic gonadotrophin; rFSH=recombinant FSH. Reproductive BioMedicine Online 2013 26, 50-58DOI: (10.1016/j.rbmo.2012.09.014) Copyright © 2012 Reproductive Healthcare Ltd. Terms and Conditions

Figure 2 Frequency distribution of (A) start day of menses; (B) start day of stimulation; (C) day HCG criterion reached; (D) day of HCG administration; (E) day of oocyte retrieval. HCG=human chorionic gonadotrophin; NS=not statistically significant. Reproductive BioMedicine Online 2013 26, 50-58DOI: (10.1016/j.rbmo.2012.09.014) Copyright © 2012 Reproductive Healthcare Ltd. Terms and Conditions

Figure 3 Histogram of day of reaching the HCG criterion (at least 3 follicles ⩾17mm on ultrasound) when stimulation starts on (A) cycle day 2 and (B) cycle day 3. HCG=human chorionic gonadotrophin. Reproductive BioMedicine Online 2013 26, 50-58DOI: (10.1016/j.rbmo.2012.09.014) Copyright © 2012 Reproductive Healthcare Ltd. Terms and Conditions

Figure 4 Histograms of day of reaching HCG criterion depending on weekday of menses and start of stimulation. On the X-axis, the number refers to the stimulation day and the letter refers to the day of the week. HCG=human chorionic gonadotrophin. Reproductive BioMedicine Online 2013 26, 50-58DOI: (10.1016/j.rbmo.2012.09.014) Copyright © 2012 Reproductive Healthcare Ltd. Terms and Conditions