Igor V. Alabugin, Trevor Harris Chem

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Photoredox-Initiated Radical Cascades Enabling Collective Synthesis of 33 Natural Products Igor V. Alabugin, Trevor Harris Chem Volume 2, Issue 6, Pages 753-755 (June 2017) DOI: 10.1016/j.chempr.2017.05.018 Copyright © 2017 Elsevier Inc. Terms and Conditions

Scheme 1 Organic Synthesis of Indole Alkaloids (A) Photoredox catalysis generates a N-centered radical that forms a 2c-3e bond after initial cyclization. (B) Stereoelectronic assistance in the key radical intermediate and the two paths for the radical cascade. (C) The variations in the intra- and intermolecular radical reactions that follow the initial C–N bond formation are the key to the diversity of natural products obtained by Qin and coworkers. Chem 2017 2, 753-755DOI: (10.1016/j.chempr.2017.05.018) Copyright © 2017 Elsevier Inc. Terms and Conditions