Congruence Between Latent Class and K-Modes Analyses in the Identification of Oncology Patients With Distinct Symptom Experiences  Nikoloas Papachristou, PhD(c), Payam Barnaghi, PhD, Bruce A. Cooper, PhD, Xiao Hu, PhD, Roma Maguire, BN, MSc, PhD, Kathi Apostolidis, Jo Armes, RN, PhD, Yvette P. Conley, PhD, Marilyn Hammer, PhD, Stylianos Katsaragakis, RN, PhD, Kord M. Kober, PhD, Jon D. Levine, MD, PhD, Lisa McCann, Bsc (Hon), MSc, PhD, Elisabeth Patiraki, RN, PhD, Steven M. Paul, PhD, Emma Ream, RN, PhD, Fay Wright, RN, PhD, Christine Miaskowski, RN, PhD  Journal of Pain and Symptom Management  Volume 55, Issue 2, Pages 318-333.e4 (February 2018) DOI: 10.1016/j.jpainsymman.2017.08.020 Copyright © 2017 American Academy of Hospice and Palliative Medicine Terms and Conditions

Fig. 1 a) Silhouette coefficient diagram for the four-class solution using latent class analysis. The sizes of the clusters in the diagram are proportional to their size inside the total sample of patients (n = 1329). The labels represent the following clusters: 0 (all low [n = 419, 31.5%]), 1 (moderate physical and lower psychological [n = 316, 23.8%]), 2 (moderate physical and higher psychological [n = 416, 31.3%]), and 3 (all high [n = 178, 13.4%]). b) Silhouette coefficient diagram for the four-cluster solution using the K-modes analysis. The sizes of the clusters in the diagram are proportional to their size inside the total sample of patients (n = 1329). The labels represent the following clusters: 0 (all low [n = 536, 40.3%]), 1 (moderate physical and lower psychological [n = 205, 15.4%]), 2 (moderate physical and higher psychological [n = 280, 21.1%]), and 3 (all high [n = 308, 23.2%]). Journal of Pain and Symptom Management 2018 55, 318-333.e4DOI: (10.1016/j.jpainsymman.2017.08.020) Copyright © 2017 American Academy of Hospice and Palliative Medicine Terms and Conditions

Fig. 2 Symptom occurrence for each of the subgroups identified using latent class analysis for the 25 symptoms on the Memorial Symptom Assessment Scale that occurred in ≥30% of the total sample (n = 1329) at time 1 (i.e., prior to next dose of chemotherapy). Journal of Pain and Symptom Management 2018 55, 318-333.e4DOI: (10.1016/j.jpainsymman.2017.08.020) Copyright © 2017 American Academy of Hospice and Palliative Medicine Terms and Conditions

Fig. 3 Symptom occurrence for each of the subgroups identified using K-modes analysis for the 25 symptoms on the Memorial Symptom Assessment Scale that occurred in ≥30% of the total sample (n = 1329) at time 1 (i.e., prior to next dose of chemotherapy). Journal of Pain and Symptom Management 2018 55, 318-333.e4DOI: (10.1016/j.jpainsymman.2017.08.020) Copyright © 2017 American Academy of Hospice and Palliative Medicine Terms and Conditions