Optimizing the culture environment and embryo manipulation to help maintain embryo developmental potential Jason E. Swain, Ph.D., Doug Carrell, Ph.D.,

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Presentation transcript:

Optimizing the culture environment and embryo manipulation to help maintain embryo developmental potential Jason E. Swain, Ph.D., Doug Carrell, Ph.D., Ana Cobo, Ph.D., Marcos Meseguer, Ph.D., Carmen Rubio, Ph.D., Gary D. Smith, Ph.D. Fertility and Sterility Volume 105, Issue 3, Pages 571-587 (March 2016) DOI: 10.1016/j.fertnstert.2016.01.035 Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 1 The stage at which biopsy is performed may impact outcomes. (A) Experimental design using randomized pairing and DNA fingerprinting to determine which embryos implanted and (B) subsequent outcomes demonstrating that day 3 biopsy reduces implantation, while blastocyst biopsy yields equivalent rates to unbiopsied embryos. (Adapted from Scott et al. [178]). Fertility and Sterility 2016 105, 571-587DOI: (10.1016/j.fertnstert.2016.01.035) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions