Excellent Outcome of Haploidentical Hematopoietic Stem Cell Transplantation in Children and Adolescents with Acquired Severe Aplastic Anemia Ho Joon.

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Presentation transcript:

Excellent Outcome of Haploidentical Hematopoietic Stem Cell Transplantation in Children and Adolescents with Acquired Severe Aplastic Anemia Ho Joon Im, Kyung Nam Koh, Eun Seok Choi, Seongsoo Jang, Seog Woon Kwon, Chan-Jeoung Park, Hyun-Sook Chi, Jong Jin Seo Biology of Blood and Marrow Transplantation Volume 19, Issue 5, Pages 754-759 (May 2013) DOI: 10.1016/j.bbmt.2013.01.023 Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Incidence of GF and aGVHD (at least grade II) according to TBI and T cell dose. (A) Graft failure (○) occurred in 3 patients in the non-TBI group. (B) aGVHD (○) developed in 3 patients (1 in the non-TBI group and 2 in the TBI group). All 3 patients had received a graft containing >1 × 106 T cells/kg. Closed circle indicates no event. Biology of Blood and Marrow Transplantation 2013 19, 754-759DOI: (10.1016/j.bbmt.2013.01.023) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Chimerism and transfusion requirements of 12 patients with SAA after HCT. Bars indicate the current length of follow-up after transplantation, with darker bars indicating the transfusion-dependent period and lighter bars indicating the transfusion-independent period. Biology of Blood and Marrow Transplantation 2013 19, 754-759DOI: (10.1016/j.bbmt.2013.01.023) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions