Direct comparison of fixed flexion, radiography and MRI in knee osteoarthritis: responsiveness data from the Osteoarthritis Initiative W. Wirth, J. Duryea,

Slides:

Advertisements

Similar presentations

Anatomical alignment, but not goniometry, predicts femorotibial cartilage loss as well as mechanical alignment: data from the Osteoarthritis Initiative

Advertisements

Knee osteoarthritis radiographic progression and associations with pain and function prior to knee arthroplasty: a multicenter comparative cohort study

Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment – data.

Subregional laminar cartilage MR spin–spin relaxation times (T2) in osteoarthritic knees with and without medial femorotibial cartilage loss – data from.

Validity and responsiveness of a new measure of knee osteophytes for osteoarthritis studies: data from the osteoarthritis initiative M. Hakky, M. Jarraya,

Functional cartilage MRI T2 mapping: evaluating the effect of age and training on knee cartilage response to running T.J. Mosher, Y. Liu, C.M. Torok

Subchondral bone marrow lesions are highly associated with, and predict subchondral bone attrition longitudinally: the MOST study F.W. Roemer, T. Neogi,

Changes in the T2 relaxation value of the tibiofemoral articular cartilage about 6 months after anterior cruciate ligament reconstruction using the double-bundle.

Two year longitudinal change and test–retest-precision of knee cartilage morphology in a pilot study for the osteoarthritis initiative F. Eckstein, M.D.,

An Investigation of High Density Mineralised Protrusions in Human Cadaveric Knees by MRI and Microtomography N.P. Thomas, N. Jeffery, R. van 't Hof,

Integration of accelerated MRI and post-processing software: a promising method for studies of knee osteoarthritis J. Duryea, C. Cheng, L.F. Schaefer,

Regional analysis of femorotibial cartilage loss in a subsample from the Osteoarthritis Initiative progression subcohort W. Wirth, M.S., M.-P. Hellio.

7th International Workshop on Osteoarthritis Imaging report: “imaging in OA – now is the time to move ahead” A. Guermazi, F. Eckstein, D. Hunter, F.

Reference values and Z-scores for subregional femorotibial cartilage thickness – results from a large population-based sample (Framingham) and comparison.

Evolution of semi-quantitative whole joint assessment of knee OA: MOAKS (MRI Osteoarthritis Knee Score) D.J. Hunter, A. Guermazi, G.H. Lo, A.J. Grainger,

The acutely ACL injured knee assessed by MRI: changes in joint fluid, bone marrow lesions, and cartilage during the first year R.B. Frobell, P.T., Ph.D.,

Association of knee pain with a reduction in thigh muscle strength – a cross-sectional analysis including 4553 osteoarthritis initiative participants

Equivalence and precision of knee cartilage morphometry between different segmentation teams, cartilage regions, and MR acquisitions E. Schneider, M.

Assessment of the radioanatomic positioning of the osteoarthritic knee in serial radiographs: comparison of three acquisition techniques M.-P. H. Le.

Sensitivity to Change of 3D Meniscal Measures in Rapidly Progressing Knee Osteoarthritis and Association With Radiographic Joint Space Width Loss M.

Predictive and concurrent validity of cartilage thickness change as a marker of knee osteoarthritis progression: data from the Osteoarthritis Initiative

Quantitatively-measured bone marrow lesions in the patellofemoral joint: distribution and association with pain C. Ratzlaff, R. Russell, J. Duryea Osteoarthritis.

Differences between X-ray and MRI-determined knee cartilage thickness in weight- bearing and non-weight-bearing conditions M. Marsh, R.B. Souza, B.T.

Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment – data.

Magnetic resonance imaging lesions are more severe and cartilage T2 relaxation time measurements are higher in isolated lateral compartment radiographic.

Presence, location, type and size of denuded areas of subchondral bone in the knee as a function of radiographic stage of OA – data from the OA initiative

F. Eckstein, A. Guermazi, G. Gold, J. Duryea, M. -P

Comparison of load responsiveness of cartilage T1rho and T2 in porcine knee joints: an experimental loading MRI study H. Hamada, T. Nishii, S. Tamura,

Vastus lateralis/vastus medialis cross-sectional area ratio impacts presence and degree of knee joint abnormalities and cartilage T2 determined with 3T.

P. -H. Tsai, M. -C. Chou, H. -S. Lee, C. -H. Lee, H. -W. Chung, Y. -C

Knee cartilage assessment with MRI (dGEMRIC) and subjective knee function in ACL injured copers: a cohort study with a 20 year follow-up P. Neuman, H.

D. J. Hunter, D. P. Beavers, F. Eckstein, A. Guermazi, R. F. Loeser, B

Articular cartilage MR imaging and thickness mapping of a loaded knee joint before and after meniscectomy Y. Song, M.S., J.M. Greve, M.S., D.R. Carter,

Relationship between knee pain and the presence, location, size and phenotype of femorotibial denuded areas of subchondral bone as visualized by MRI

T. Nozaki, Y. Kaneko, H. Yu, K. Kaneshiro, R. Schwarzkopf, T. Hara, H

Subregional femorotibial cartilage morphology in women – comparison between healthy controls and participants with different grades of radiographic knee.

Baseline knee adduction and flexion moments during walking are both associated with 5 year cartilage changes in patients with medial knee osteoarthritis

Baseline and longitudinal change in isometric muscle strength prior to radiographic progression in osteoarthritic and pre-osteoarthritic knees – data.

Osteoarthritis may not be a one-way-road of cartilage loss – comparison of spatial patterns of cartilage change between osteoarthritic and healthy knees

Comparison of 1-year vs 2-year change in regional cartilage thickness in osteoarthritis results from 346 participants from the Osteoarthritis Initiative

Pre-radiographic osteoarthritic changes are highly prevalent in the medial patella and medial posterior femur in older persons: Framingham OA study D.

Anatomical alignment, but not goniometry, predicts femorotibial cartilage loss as well as mechanical alignment: data from the Osteoarthritis Initiative

The association of prevalent medial meniscal pathology with cartilage loss in the medial tibiofemoral compartment over a 2-year period M.D. Crema, A.

Bone marrow lesions and joint effusion are strongly and independently associated with weight-bearing pain in knee osteoarthritis: data from the osteoarthritis.

Rates and sensitivity of knee cartilage thickness loss in specific central reading radiographic strata from the osteoarthritis initiative S. Maschek,

G. Neumann, D. Hunter, M. Nevitt, L. B. Chibnik, K. Kwoh, H. Chen, T

Structural changes in the knee during weight loss maintenance after a significant weight loss in obese patients with osteoarthritis: a report of secondary.

Quantitative measurement of medial femoral knee cartilage volume – analysis of the OA Biomarkers Consortium FNIH Study cohort L.F. Schaefer, M. Sury,

Baseline radiographic osteoarthritis and semi-quantitatively assessed meniscal damage and extrusion and cartilage damage on MRI is related to quantitatively.

Magnetic resonance imaging (MRI)-defined cartilage degeneration and joint pain are associated with poor physical function in knee osteoarthritis – the.

How do short-term rates of femorotibial cartilage change compare to long-term changes? Four year follow-up data from the osteoarthritis initiative F.

Progression of cartilage damage and meniscal pathology over 30 months is associated with an increase in radiographic tibiofemoral joint space narrowing.

Comparison of BLOKS and WORMS scoring systems part I

MRI-derived T2 relaxation times and cartilage morphometry of the tibio-femoral joint in subjects with and without osteoarthritis during a 1-year follow-up

Region of interest analysis: by selecting regions with denuded areas can we detect greater amounts of change? D.J. Hunter, L. Li, Y.Q. Zhang, S. Totterman,

S. N. Edd, H. Babel, R. Colotti, R. B. van Heeswijk, L. C. Pereira, B

D.J. Hunter Osteoarthritis and Cartilage

Synovitis and the risk of knee osteoarthritis: the MOST Study

I. G. Otterness, Ph. D. , M. -P. H. Le Graverand, M. D. , Ph. D. , F

Magnitude and regional distribution of cartilage loss associated with grades of joint space narrowing in radiographic osteoarthritis – data from the Osteoarthritis.

Location-specific hip joint space width for progression of hip osteoarthritis – Data from the Osteoarthritis Initiative C. Ratzlaff, C. Van Wyngaarden,

Trajectory of cartilage loss within 4 years of knee replacement – a nested case–control study from the Osteoarthritis Initiative F. Eckstein, R.M. Boudreau,

M. Hudelmaier, W. Wirth Osteoarthritis and Cartilage

MRI-based extended ordered values more efficiently differentiate cartilage loss in knees with and without joint space narrowing than region-specific approaches.

Longitudinal assessment of femoral knee cartilage quality using contrast enhanced MRI (dGEMRIC) in patients with anterior cruciate ligament injury – comparison.

The acutely ACL injured knee assessed by MRI: are large volume traumatic bone marrow lesions a sign of severe compression injury? R.B. Frobell, P.T.,

Thigh muscle cross-sectional areas and strength in knees with early vs knees without radiographic knee osteoarthritis: a between-knee, within-person comparison

Is the atrophic phenotype of tibiofemoral osteoarthritis associated with faster progression of disease? The MOST study M.D. Crema, D.T. Felson, A. Guermazi,

Altered biomechanics and cartilage health changes in bilateral knees following unilateral ACL reconstruction: a 2-year follow-up J.K. Ochoa, K. Amano,

Tibial coverage, meniscus position, size and damage in knees discordant for joint space narrowing – data from the Osteoarthritis Initiative K. Bloecker,

Presentation transcript:

Direct comparison of fixed flexion, radiography and MRI in knee osteoarthritis: responsiveness data from the Osteoarthritis Initiative W. Wirth, J. Duryea, M.-P. Hellio Le Graverand, M.R. John, M. Nevitt, R.J. Buck, F. Eckstein Osteoarthritis and Cartilage Volume 21, Issue 1, Pages 117-125 (January 2013) DOI: 10.1016/j.joca.2012.10.017 Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 (A) Illustration showing the radiography-based measurement of the mJSW and of the JSW at the central fixed-location JSW(x = 0.225). (B) Illustration showing the coronal FLASH MRI-based measurement in the MFTC and in the most sensitive subregion of the MFTC (cMFTC). (C) Illustration showing the sagittal DESS MRI-based measurement in the MFTC and in the most sensitive subregion of the MFTC (cMFTC). (D) Bar graph showing the sensitivity to change (SRM = MC/SD of the change) for mJSW, MFTC, and the most sensitive fixed-location JSW(x) in the FLASH sample over 12 months [12 M, JSW(x) = JSW(x = 0.25)], in the DESS sample over 12 M [JSW(x) = JSW(x = 0.225)], and in the DESS sample over 24 months [24 M, JSW(x) = JSW(x = 0.225)]. The DESS sample over 12 months is a sub-sample of the 24 months cohort, for which a complete set of 12 months measurements was available. (E) Illustration showing the central (c), external (e), internal (i), anterior (a), and posterior subregions (p) computed in the MT and lateral tibia (LT) and in the central, weight-bearing part if the medial (cMF) and lateral (cLF) femoral condyle (only central, external, and internal subregions). Osteoarthritis and Cartilage 2013 21, 117-125DOI: (10.1016/j.joca.2012.10.017) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions