Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331 288.

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Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331 288 participants    The Lancet Diabetes & Endocrinology  Volume 3, Issue 8, Pages 624-637 (August 2015) DOI: 10.1016/S2213-8587(15)00129-1 Copyright © 2015 NCD Risk Factor Collaboration. Open Access article distributed under the terms of CC BY Terms and Conditions

Figure 1 Study and data inclusion FPG=fasting plasma glucose. 2hOGTT=2-h oral glucose tolerance test. *The meta-analyses used inverse of variance as survey weights; sensitivity or specificity of either 0% or 100% would make the corresponding variance zero, and therefore the inverse of variance infinite. The Lancet Diabetes & Endocrinology 2015 3, 624-637DOI: (10.1016/S2213-8587(15)00129-1) Copyright © 2015 NCD Risk Factor Collaboration. Open Access article distributed under the terms of CC BY Terms and Conditions

Figure 2 Prevalence of diabetes defined by FPG-or-2hOGTT versus by FPG only FPG-or-2hOGTT definition was FPG 7·0 mmol/L or more, or 2hOGTT 11·1 mmol/L or more, or history of diabetes or using insulin or oral hypoglycaemic drugs. FPG only definition was FPG 7·0 mmol/L or more, or history of diabetes or using insulin or oral hypoglycaemic drugs. Each point shows one age–sex group in one survey. Table 1 shows the relation summarised as regression coefficients. FPG=fasting plasma glucose. 2hOGTT=2-h oral glucose tolerance test. The Lancet Diabetes & Endocrinology 2015 3, 624-637DOI: (10.1016/S2213-8587(15)00129-1) Copyright © 2015 NCD Risk Factor Collaboration. Open Access article distributed under the terms of CC BY Terms and Conditions

Figure 3 Prevalence of diabetes defined by HbA1c only versus prevalence defined by (A) FPG only, and (B) FPG-or-2hOGTT HbA1c definition was HbA1c 6·5% or more, or history of diabetes, or using insulin or oral hypoglycaemic drugs. FPG only definition was FPG 7·0 mmol/L or more, or history of diabetes or using insulin or oral hypoglycaemic drugs. FPG-or-2hOGTT definition was FPG 7·0 mmol/L or more, or 2hOGTT 11·1 mmol/L or more, or history of diabetes or using insulin or oral hypoglycaemic drugs. Each point shows one age–sex group in one survey. Table 2 shows the relations summarised as regression coefficients. FPG=fasting plasma glucose. 2hOGTT=2-h oral glucose tolerance test. The Lancet Diabetes & Endocrinology 2015 3, 624-637DOI: (10.1016/S2213-8587(15)00129-1) Copyright © 2015 NCD Risk Factor Collaboration. Open Access article distributed under the terms of CC BY Terms and Conditions