A 45-year-old smoking man diagnosed with desquamative interstitial pneumonia (DIP) by a) cryo-transbronchial lung biopsy (haematoxylin–eosin stain) showing.

Slides:

Advertisements

Similar presentations

Representative images of a, b) vehicle control and c–f) NiO nanoparticles (NPs) 4 weeks post-instillation. a) Normal alveolar structure consisting of thin.

Advertisements

Pathological alterations in idiopathic pulmonary fibrosis (IPF).

Pathological findings

Echocardiography view

Discoidin domain receptor (DDR)2 protein was highly expressed in the lungs of patients with interstitial lung disease (ILD). Discoidin domain receptor.

Overall survival from enrolment according to operating rule and scenario of organ scarcity for a) scenario R96 (i.e. 96 organs for 100 virtual patients.

Serial imaging while on immunosuppressive therapy (two subjects).

Compliance of the respiratory system (Crs) at baseline and 0 h, 1 h and 2 h following lung volume recruitment. a) Absolute Crs in the respiratory muscle.

Flowchart for calculating the relative risk (RR) for cancer X and lung cancer (LC). Flowchart for calculating the relative risk (RR) for cancer X and lung.

Distribution of forced expiratory volume in 1 s (FEV1) relative to Global Lung Function Initiative reference values (GLI2012) [10] expressed as FEV1 %

Kaplan–Meier curves for a, b) progression-free survival (PFS) and c, d) overall survival (OS) in a, c) large-cell neuroendocrine carcinoma patients and.

Prevalence of true-positive, false-negative and false-positive cases of chronic obstructive pulmonary disease identified with the fixed-limit Global Initiative.

A) CT scan of patient number 1, before pembrolizumab; b) CT scan of patient number 1, after 11 pembrolizumab infusions; c) CT scan of patient number 1,

Survival without tracheostomy

Symptoms measured by Edmonton Symptom Assessment Scale according to modified Medical Research Council (mMRC) dyspnoea scale groups. Symptoms measured by.

Kaplan–Meier curve for the time until the development of lung cancer in patients with idiopathic pulmonary fibrosis. Kaplan–Meier curve for the time until.

Distribution of lower extremity artery disease (LEAD) Fontaine stages over the combined chronic obstructive pulmonary disease (COPD) Global Initiative.

Representative images of immunohistochemical staining of discoidin domain receptor (DDR)2 in interstitial lung disease (ILD) other than idiopathic pulmonary.

Bland–Altman plot of slopes of measurement 1 versus 2

Comparative expression of discoidin domain receptors (DDRs) between healthy lung tissues and those from different types of interstitial lung disease (ILD):

Volume 144, Issue 1, Pages (July 2013)

Bland–Altman comparison of lung clearance index (LCI) from multiple breath wash-out following open and modified closed circuit wash-in for both healthy.

SDS–PAGE and immunoblots of purified IgG for citrullination and carbamylation. a) Representative Coomassie-blue-stained isolated total IgG from patients.

Programmed cell death ligand-1 (PD-L1) expression of alveolar macrophages. Programmed cell death ligand-1 (PD-L1) expression of alveolar macrophages. (A)

Venn diagram showing the overlap between the various chronic obstructive pulmonary disease (COPD) diagnoses: self-reported physician-diagnosed, fixed ratio.

Lung histopathology from two subjects demonstrating either capillaritis or prior alveolar haemorrhage. Lung histopathology from two subjects demonstrating.

Kaplan–Meier survival curves of all-cause mortality in patients with idiopathic pulmonary fibrosis (IPF). Kaplan–Meier survival curves of all-cause mortality.

A) Axial computed tomography (CT) showing mild thickening of bronchial walls (arrows) in a woman with Sjögren's syndrome. b) Chronic cough and recurrent.

A white elephant or the elephant in the room

a) Chest radiograph showing bilateral coarse interstitial shadowing

Nonspecific interstitial pneumonia in a woman a, c) at the time of Sjögren's syndrome diagnosis and b) after 3 years. a, b) High-resolution computed tomography.

A) Usual interstitial pneumonia in a 69-year-old woman with primary Sjögren's syndrome. a) Usual interstitial pneumonia in a 69-year-old woman with primary.

A) Low magnification histopathological biopsy showing typical features of usual interstitial pneumonia pattern with a heterogeneous appearance and areas.

The variability of probability of that the length of stay is longer than the median by country. The variability of probability of that the length of stay.

Induced pleurodesis depending on the two techniques

A–c) This lung biopsy from a 55-year-old male patient, who was a nonsmoker, shows a typical desquamative interstitial pneumonia pattern. a–c) This lung.

A) The flexible 1.9 mm diameter and 900 mm length cryoprobe, b) connected to the cryotherapy equipment. c) Marks on the distal area of the probe (1 cm.

Most frequent words and phrases based on user comments about the registry. Most frequent words and phrases based on user comments about the registry. Word.

Transbronchial lung biopsy microscopic slide of a) lung tissue showing a granulomatous inflammation with giant cell reaction and b) lung tissue under polarised.

Phosphorylation levels of discoidin domain receptor (DDR)2.

Selection of patients: 248 consecutive patients with newly diagnosed pre-capillary pulmonary hypertension were included in the study. Selection of patients:

a) Factors influencing the risk of bleeding

Flow–volume loop analysis

Microphotographs (×20) of endobronchial biopsies from a) healthy control, b) mildly asthmatic and c) severe asthmatic airways demonstrating increased thickness.

Consolidated Standards of Reporting Trials diagram.

A summary of the pathogenesis, pathophysiology and clinical implications of the pulmonary vascular and cardiac abnormalities in interstitial lung disease.

A) Respiratory bronchiolitis: the intra-alveolar accumulation of finely pigmented macrophages (smoker’s macrophages) (haematoxylin and eosin, 400×). a)

A) 18-fluorodeoxyglucose positron emission tomography-computed tomography in a 72-year-old male revealed pulmonary nodules in the lower lobes. a) 18-fluorodeoxyglucose.

Simplified diagram of the multidisciplinary process to diagnose interstitial lung disease, including a clinician, radiologist, pathologist and also a geneticist:

Forest plot of adjusted odds ratios (with 95% confidence intervals) from multivariable multinomial logistic regression analysis (table 4), by number of.

A) Axial, 5-mm slice thickness computed tomography (CT) image through the upper lobes at the level of the aortic arch. a) Axial, 5-mm slice thickness computed.

Endobronchial biopsy from case 2 showing sheets of epitheloid macrophages without giant cells, mixed with other chronic inflammatory cells. Endobronchial.

Outline of the distal lung regions in haematoxylin and eosin-stained lung tissue [115, 116] showing the inner airway wall (green arrowheads), smooth muscle.

Weekly pneumococcal community-acquired pneumonia incidence rates over 5 years, with delineated school holiday periods by year. a) Year 1 (September 2008–2009).

Transbronchial cryobiopsy (TBCx)

Differences in a) functional residual capacity (FRC) and b) lung clearance index (LCI) when using all trials in comparison with only the first two trials.

Example of thin parenchymal section computed tomography findings in desquamative interstitial pneumonia: patchy ground-glass attenuation with a peripheral.

Percentage of women using snus and/or cigarette smoke during pregnancy based on self-reported time for stopping from those who completed both 18-week and.

A) Small pulmonary arteries within a fibrotic area (usual interstitial pneumonia lung). a) Small pulmonary arteries within a fibrotic area (usual interstitial.

Distribution of patients in the first- or second-year follow-up according to the number of acute exacerbations of chronic obstructive pulmonary disease.

Procedure for the diagnosis of interstitial lung diseases.

Composition of the most common clusters at the a) onset of the first acute respiratory tract infection (swab A) and b) 3 weeks later (swab B) illustrated.

Open lung biopsy specimen showing an inflammation with thickened interalveolar septa and the inflammatory infiltration of mononuclear cells (areas of a.

Comparison of cancer-specific survival in patients with nonsmall cell lung cancer detected incidentally by computed tomography (CT) (n=41) or chest radiography.

Prevalence of acute myocardial infarction (AMI) or other cardiovascular events (CVEs) according to a) Pneumonia Severity Index (PSI) risk classes and b)

Effects of reslizumab on lung function (forced expiratory volume in 1 s; FEV1) in Global Initiative for Asthma (GINA) Step 4 and 5 patients. Effects of.

Percentage of positive results by pathogen among study patients with identified pathogens. “Other” includes respiratory viruses, Stenotrophomonas, Prevotella,

Biomarker levels at hospital admission, clinical stabilisation and 6-week follow-up in 267 hospitalised patients with community-acquired pneumonia. a)

High-resolution computed tomography images of smoking-related interstitial lung diseases (ILDs). a) Pulmonary Langerhans cell histiocytosis, b) respiratory.

A) Smokers’ macrophages show a fine, golden haemosiderin cytoplasmic pigment; b) in respiratory bronchiolitis (RB), smokers’ macrophages are located in.

Presentation transcript:

A 45-year-old smoking man diagnosed with desquamative interstitial pneumonia (DIP) by a) cryo-transbronchial lung biopsy (haematoxylin–eosin stain) showing b) thick alveolar septa filled by numerous macrophages with c) CD68 staining. A 45-year-old smoking man diagnosed with desquamative interstitial pneumonia (DIP) by a) cryo-transbronchial lung biopsy (haematoxylin–eosin stain) showing b) thick alveolar septa filled by numerous macrophages with c) CD68 staining. A 67-year-old man diagnosed with silicosis by d) cryo-transbronchial lung biopsy showing e) a silicotic nodule (black arrow) and f) silica crystals with polarised light (white arrow). Antonio Bango-Álvarez et al. ERJ Open Res 2017;3:00148-2016 ©2017 by European Respiratory Society