Spasmolytic effects of prostaglandin E1 on serotonin-induced bronchoconstriction and pulmonary hypertension in dogs Y. Hashimoto, K. Hirota, H. Yoshioka, E. Hashiba, T. Kudo, H. Ishihara, A. Matsuki British Journal of Anaesthesia Volume 85, Issue 3, Pages 460-462 (September 2000) DOI: 10.1093/bja/85.3.460 Copyright © 2000 British Journal of Anaesthesia Terms and Conditions
Fig 1 Effects of prostaglandin E1 on 5HT-induced pulmonary hypertension (A) and bronchoconstriction (B). Application of 5HT (10 μg kg−1 + 1.0 mg kg−1 h−1) is indicated by the solid bar. *, #, $ and + indicate P<0.05 and **, ##, $$ and ++ indicate P<0.01 compared with 0 (saline) and PGE1 0.01, 0.1 and 1.0 μg kg−1, respectively. All values are expressed as mean±sem. British Journal of Anaesthesia 2000 85, 460-462DOI: (10.1093/bja/85.3.460) Copyright © 2000 British Journal of Anaesthesia Terms and Conditions