Distribution of VSMCs on the surface of embolic devices.

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Presentation transcript:

Distribution of VSMCs on the surface of embolic devices. Distribution of VSMCs on the surface of embolic devices. Images are argon-laser fluorescence confocal micrographs of embolic devices obtained after monopulse exposure assays (original magnification ×40). Wide solid straight arrows indicate loops of the nitinol coil; curved arrows, collagen fibers; thin solid straight arrows, live cells; open arrows, dead cells.A, CFBs exposed to an initial VSMC concentration of 2.6 × 104 cells per milliliter. VSMCs are spread over the convex surfaces of individual fibers and within the troughs between fibers.B, Nitinol coils with a helical pitch of 50 μm exposed to an initial VSMC concentration of 2.6 × 105 cells per milliliter. VSMCs are preferentially distributed in the troughs between coil loops.C, CINCs with a helical pitch of 250 μm exposed to an initial VSMC concentration of 2.6 × 105 cells per milliliter. VSMCs are focally concentrated on the surfaces of collagen fibers between consecutive coil loops. Todd Abruzzo et al. AJNR Am J Neuroradiol 2002;23:674-681 ©2002 by American Society of Neuroradiology