Effectiveness of 80% vs 30–35% fraction of inspired oxygen in patients undergoing surgery: an updated systematic review and meta-analysis Stijn de Jonge,

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Effectiveness of 80% vs 30–35% fraction of inspired oxygen in patients undergoing surgery: an updated systematic review and meta-analysis Stijn de Jonge, Matthias Egger, Asad Latif, Yoon Kong Loke, Sean Berenholtz, Marja Boermeester, Benedetta Allegranzi, Joseph Solomkin British Journal of Anaesthesia Volume 122, Issue 3, Pages 325-334 (March 2019) DOI: 10.1016/j.bja.2018.11.024 Copyright © 2018 World Health Organization Terms and Conditions

Fig 1 Flow chart of study selection.46 Numbers between brackets represent the original search dating from 2014. SSI, surgical site infection. British Journal of Anaesthesia 2019 122, 325-334DOI: (10.1016/j.bja.2018.11.024) Copyright © 2018 World Health Organization Terms and Conditions

Fig 2 Risk-of-bias summary. Green bubbles represent low risk of bias, yellow bubbles represent unclear risk of bias, and red bubbles represent high risk of bias. British Journal of Anaesthesia 2019 122, 325-334DOI: (10.1016/j.bja.2018.11.024) Copyright © 2018 World Health Organization Terms and Conditions

Fig 3 Forest plot analysis by delivery of the intervention. The X-axis represents relative risk (RR); each row on the Y-axis represents an individual study. The solid diamonds and horizontal lines represent point estimates and corresponding 95% confidence intervals (CIs) of the individual studies, respectively. The transparent diamonds represent the pooled estimate and 95% confidence interval of each subgroup, and the overall analysis. British Journal of Anaesthesia 2019 122, 325-334DOI: (10.1016/j.bja.2018.11.024) Copyright © 2018 World Health Organization Terms and Conditions