Volume 103, Issue 6, Pages (June 1993)

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Volume 103, Issue 6, Pages 1863-1872 (June 1993) Chronic Obstructive Pulmonary Disease Early Intervention Trial (Lung Health Study) A. Sonia Buist, M.D., John E. Connett, Ph.D., R. Drew Miller, M.D., F.C.C.P., Richard E. Kanner, M.D., F.C.C.P., Gregory R. Owens, M.D., F.C.C.P., Helen T. Voelker CHEST Volume 103, Issue 6, Pages 1863-1872 (June 1993) DOI: 10.1378/chest.103.6.1863 Copyright © 1993 The American College of Chest Physicians Terms and Conditions

Figure 1. Level of education of subjects. CHEST 1993 103, 1863-1872DOI: (10.1378/chest.103.6.1863) Copyright © 1993 The American College of Chest Physicians Terms and Conditions

Figure 2. Average number of cigarettes smoked per day at screen 1 by age at randomization and gender. CHEST 1993 103, 1863-1872DOI: (10.1378/chest.103.6.1863) Copyright © 1993 The American College of Chest Physicians Terms and Conditions

Figure 3. Mean FEV1 percent predicted and FEV1/ FVC percent at screen 2 by age at randomization and gender. CHEST 1993 103, 1863-1872DOI: (10.1378/chest.103.6.1863) Copyright © 1993 The American College of Chest Physicians Terms and Conditions

Figure 4. Percent of LHS participants reporting wheezing with a cold by age (based on responses to question 10A.1 in ATS questionnaire15). CHEST 1993 103, 1863-1872DOI: (10.1378/chest.103.6.1863) Copyright © 1993 The American College of Chest Physicians Terms and Conditions

Figure 5. Participants reporting wheezing most days or nights (based on response to question 10A.2 in ATS questionnaire15). CHEST 1993 103, 1863-1872DOI: (10.1378/chest.103.6.1863) Copyright © 1993 The American College of Chest Physicians Terms and Conditions

Figure 6. Frequency distribution of increase in FEV1 (as percentage of baseline) in response to inhaled isoproterenol. CHEST 1993 103, 1863-1872DOI: (10.1378/chest.103.6.1863) Copyright © 1993 The American College of Chest Physicians Terms and Conditions

Figure 7. Cumulative percent of LHS participants with at least 20 percent decrease in FEV, in response to increasing doses of inhaled methacholine. CHEST 1993 103, 1863-1872DOI: (10.1378/chest.103.6.1863) Copyright © 1993 The American College of Chest Physicians Terms and Conditions