Quizpage answers june 2003 American Journal of Kidney Diseases   American Journal of Kidney Diseases  Volume 41, Issue 6, Pages A48-A51 (June 2003) DOI: 10.1016/S0272-6386(03)00514-6 Copyright © 2003 Terms and Conditions

Figure 17A What do you see by light microscopy? American Journal of Kidney Diseases 2003 41, A48-A51DOI: (10.1016/S0272-6386(03)00514-6) Copyright © 2003 Terms and Conditions

Figure 17B What do you see by electron microscopy? American Journal of Kidney Diseases 2003 41, A48-A51DOI: (10.1016/S0272-6386(03)00514-6) Copyright © 2003 Terms and Conditions

Figure 17C What additional lesion can you detect? American Journal of Kidney Diseases 2003 41, A48-A51DOI: (10.1016/S0272-6386(03)00514-6) Copyright © 2003 Terms and Conditions

Figure 17D Further examination revealed focal areas with numerous eosinophils in the areas of edema and infiltrate, in addition to the lymphocytes and plasma cells (Fig 17D, hematoxylin and eosin stain, original magnification ×400). These findings are diagnostic of a superimposed acute interstitial nephritis, with the numerous eosinophils strongly suggesting hypersensitivity-induced etiology. This diagnosis was also verified by the clinical follow-up, where removal of the likely offending agent (in this case ciprofloxacin) led to return of creatinine to baseline levels. American Journal of Kidney Diseases 2003 41, A48-A51DOI: (10.1016/S0272-6386(03)00514-6) Copyright © 2003 Terms and Conditions