Relationship between leukocytes recruitment and risk of rebleeding in patients with peptic ulcers  Oksana Sulaieva, Victoriia Deliy, Stanislav Zharikov  Pathophysiology  Volume 22, Issue 4, Pages 175-182 (December 2015) DOI: 10.1016/j.pathophys.2015.07.002 Copyright © 2015 Terms and Conditions

Fig. 1 Elevation of PMN count in the ulcer margin of patients with a sustained hemostasis (1st group) and rebleeders (2nd group). A – Chart demonstrates PMN count in adjacent to ulcer tissues among patients of the 1st and 2nd groups at the time of their hospital admission (Me±m; CI). B – Ischemia and inflammation in the gastric ulcer margin among patients of the 1st group. C – Deep infiltration of gastric mucosa with PMNs among patients of the 2nd group. H&E staining. Pathophysiology 2015 22, 175-182DOI: (10.1016/j.pathophys.2015.07.002) Copyright © 2015 Terms and Conditions

Fig. 2 Macrophages density in ulcer margin among patients with acute ulcer bleeding. A – Chart demonstrates PMN count in adjacent to ulcer tissues among patients of the 1st and 2nd groups at the time of their hospital admission (Me±m; CI). B – Histological specimens of marginal zone of ulcer of the 1st group patients under immunohistochemistry (CD 68). С and D – Increased number of macrophages in the gastric (C) and duodenal (D) ulcer margin among patients of the 2st group. Immunohistochemistry (CD68). Pathophysiology 2015 22, 175-182DOI: (10.1016/j.pathophys.2015.07.002) Copyright © 2015 Terms and Conditions

Fig. 3 Impact of leukocytes on platelets’ aggregation induced with collagen among patients with acute ulcer bleeding (%). Description: the collagen-induced platelet aggregation (%) is shown under different conditions: when platelets were incubated with collagen alone (Pl) or under preliminary co-incubation of platelets with leukocytes (Pl+Lc). Pathophysiology 2015 22, 175-182DOI: (10.1016/j.pathophys.2015.07.002) Copyright © 2015 Terms and Conditions