Use of F-18 Fluorodeoxyglucose Positron Emission Tomography With Dual-Phase Imaging to Identify Intraductal Papillary Mucinous Neoplasm  Masayoshi Saito, Takeshi Ishihara, Motohisa Tada, Toshio Tsuyuguchi, Rintaro Mikata, Yuji Sakai, Katsunobu Tawada, Harutoshi Sugiyama, Jo Kurosawa, Masayuki Otsuka, Yoshitaka Uchida, Katsuhiro Uchiyama, Masaru Miyazaki, Osamu Yokosuka  Clinical Gastroenterology and Hepatology  Volume 11, Issue 2, Pages 181-186 (February 2013) DOI: 10.1016/j.cgh.2012.10.037 Copyright © 2013 AGA Institute Terms and Conditions

Figure 1 Correlation between pathologic type IPMN and SUVmax in the early phase. The SUVmax on early phase of LGD and IGD, HGD, and invasive carcinoma was 1.5 ± 0.4, 2.6 ± 0.9, and 4.6 ± 2.7, respectively. The SUVmax of HGD was statistically higher than those of LGD and IGD (P < .001). The SUVmax of invasive carcinoma was also higher than that of HGD (P < .001). *Mann–Whitney U test. Clinical Gastroenterology and Hepatology 2013 11, 181-186DOI: (10.1016/j.cgh.2012.10.037) Copyright © 2013 AGA Institute Terms and Conditions

Figure 2 Results for 18 patients in whom dual-phase FDG-PET/CT was performed. Twelve of 13 malignant IPMNs (92.3%) had further increase in SUVmax; 3 of 5 benign IPMNs (60.0%) had decrease in SUVmax on delayed phase. The RI of malignant and benign IPMNs was 19.6 ± 17.8 and −2.6 ± 12.9 (P = .030). If a combination of the SUVmax cutoff value of 2.0 in the early phase and the RI value of −10.0 for detection of malignant IPMN was used, one false-positive adenoma case (SUVmax: early 2.4, delayed 2.0) may be diagnosed as benign IPMN. *Mann–Whitney U test. Clinical Gastroenterology and Hepatology 2013 11, 181-186DOI: (10.1016/j.cgh.2012.10.037) Copyright © 2013 AGA Institute Terms and Conditions