Number of 0.5-Mb windows with chromosome lesions that reached statistical significance across patients in early (BE early and BE instability) and late.

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Number of 0.5-Mb windows with chromosome lesions that reached statistical significance across patients in early (BE early and BE instability) and late (advanced BE and EA) stages of neoplastic progression. Number of 0.5-Mb windows with chromosome lesions that reached statistical significance across patients in early (BE early and BE instability) and late (advanced BE and EA) stages of neoplastic progression. White, the number of 0.5-Mb windows that reached statistical significance in early-stage (BE early and BE instability) samples only but were not significant in late-stage samples. Intersection of white and dotted, the number of events that reached statistical significance both in early-stage (BE early and BE instability) and late-stage (advanced BE and EA) samples. Dotted, the number of events that reached statistical significance in late-stage (advanced BE and EA) samples only but were not significant in early stages. A, gain. B, loss. C, LOH. Xiaohong Li et al. Cancer Prev Res 2008;1:413-423 ©2008 by American Association for Cancer Research