Acceptability and feasibility of a screen-and-treat programme for hepatitis B virus infection in The Gambia: the Prevention of Liver Fibrosis and Cancer.

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Presentation transcript:

Acceptability and feasibility of a screen-and-treat programme for hepatitis B virus infection in The Gambia: the Prevention of Liver Fibrosis and Cancer in Africa (PROLIFICA) study Maud Lemoine, PhD, Yusuke Shimakawa, PhD, Ramou Njie, PhD, Makie Taal, MSc, Gibril Ndow, MD, Isabelle Chemin, PhD, Sumantra Ghosh, PhD, Harr F Njai, PhD, Adam Jeng, BSc, Amina Sow, PhD, Prof Coumba Toure-Kane, PhD, Prof Souleymane Mboup, PhD, Penda Suso, BSc, Saydiba Tamba, Abdullah Jatta, Louise Sarr, MD, Aboubacar Kambi, MD, William Stanger, Bsc, Shevanthi Nayagam, MD, Jessica Howell, PhD, Liliane Mpabanzi, PhD, Prof Ousman Nyan, MD, Prof Tumani Corrah, PhD, Prof Hilton Whittle, PhD, Prof Simon D Taylor-Robinson, PhD, Prof Umberto D'Alessandro, PhD, Maimuna Mendy, PhD, Prof Mark R Thursz, MD The Lancet Global Health Volume 4, Issue 8, Pages e559-e567 (August 2016) DOI: 10.1016/S2214-109X(16)30130-9 Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 1 Locations of the urban and rural community areas selected for screening The Lancet Global Health 2016 4, e559-e567DOI: (10.1016/S2214-109X(16)30130-9) Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 2 Flow chart of study participants *Other reasons for non-participation were too busy (n=65); feeling ill (n=55); husband refusal (women only; n=43); afraid of bleeding (n=21); no trust in Medical Research Council (n=11); already tested before (n=4); and refusal without revealing any specific reason (n=157). †Estimates accounted for survey design. ‡Estimates accounted for survey design and non-attendance to the programme. HBsAg=hepatitis B surface antigen. The Lancet Global Health 2016 4, e559-e567DOI: (10.1016/S2214-109X(16)30130-9) Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 3 Prevalence of HBsAg positivity by age and sex in blood bank and community screening Error bars represent 95% CIs. For blood bank screening, the analysis was restricted to males because of the small number of female blood donors (n=36). Error bars omitted for male donors aged 60 years or older because of small population (n=11). HBsAg=hepatitis B surface antigen. The Lancet Global Health 2016 4, e559-e567DOI: (10.1016/S2214-109X(16)30130-9) Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions