Factors Associated With Attrition in a Multicenter Longitudinal Observational Study of Patients With Advanced Cancer  Pedro E. Perez-Cruz, MD, MPH, Omar Shamieh, MD, MBA, Carlos Eduardo Paiva, MD, PhD, Jung Hye Kwon, MD, PhD, Mary Ann Muckaden, MD, Eduardo Bruera, MD, David Hui, MSc, MD  Journal of Pain and Symptom Management  Volume 55, Issue 3, Pages 938-945 (March 2018) DOI: 10.1016/j.jpainsymman.2017.11.009 Copyright © 2017 American Academy of Hospice and Palliative Medicine Terms and Conditions

Fig. 1 Association between Karnofsky Performance Status and attrition. Considering KPS as a categorical variable, we estimated the odds of dropping out from the study using KPS >90 as baseline. The ORs (95% CI; P-value) for each category were: KPS = 80: 1.73 (0.90–3.31; 0.1)/KPS = 70: 2.75 (1.48–5.13; 0.001)/KPS = 60: 2.82 (1.48–5.40; 0.002)/KPS<50: 7.36 (3.80–14.29; <0.001). We also estimated the odds of dropping out from the study by KPS, assuming that KPS was a continuous variable: OR 1.55 (1.35–1.76; P < 0.001) per 10-point decrease in the KPS score. KPS = Karnofsky Performance Status; OR = odds ratio. Journal of Pain and Symptom Management 2018 55, 938-945DOI: (10.1016/j.jpainsymman.2017.11.009) Copyright © 2017 American Academy of Hospice and Palliative Medicine Terms and Conditions

Fig. 2 Dropout percentage by Global Distress Score–Physical. Journal of Pain and Symptom Management 2018 55, 938-945DOI: (10.1016/j.jpainsymman.2017.11.009) Copyright © 2017 American Academy of Hospice and Palliative Medicine Terms and Conditions