Ladislav Rampasek, Anna Goldenberg  Cell 

Slides:



Advertisements
Similar presentations
Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester Transfer Shaun K. Olsen, Christopher D. Lima Molecular Cell Volume 49, Issue 5, Pages.
Advertisements

The Bacterial DnaC Helicase Loader Is a DnaB Ring Breaker Ernesto Arias-Palomo, Valerie L. O’Shea, Iris V. Hood, James M. Berger Cell Volume 153, Issue.
Profiling by Image Registration Reveals Common Origin of Annelid Mushroom Bodies and Vertebrate Pallium Raju Tomer, Alexandru S. Denes, Kristin Tessmar-Raible,
SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration Amit R. Reddi, Valeria C. Culotta Cell Volume 152, Issue 1, Pages (January.
Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.
The RAG Recombinase Dictates Functional Heterogeneity and Cellular Fitness in Natural Killer Cells Jenny M. Karo, David G. Schatz, Joseph C. Sun Cell Volume.
The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity Jenni Durieux, Suzanne Wolff, Andrew Dillin Cell Volume 144, Issue 1, Pages.
Local Translation of Extranuclear Lamin B Promotes Axon Maintenance Byung C. Yoon, Hosung Jung, Asha Dwivedy, Catherine M. O'Hare, Krishna H. Zivraj, Christine.
Bleach Activates a Redox-Regulated Chaperone by Oxidative Protein Unfolding J. Winter, M. Ilbert, P.C.F. Graf, D. Özcelik, U. Jakob Cell Volume 135, Issue.
What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell
Treatment of Obesity with Celastrol
Mitoconfusion: Noncanonical Functioning of Dynamism Factors in Static Mitochondria of the Heart Moshi Song, Gerald W. Dorn Cell Metabolism Volume 21, Issue.
Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni
Common Sense about Taste: From Mammals to Insects David A. Yarmolinsky, Charles S. Zuker, Nicholas J.P. Ryba Cell Volume 139, Issue 2, Pages (October.
Genome-wide Single-Cell Analysis of Recombination Activity and De Novo Mutation Rates in Human Sperm Jianbin Wang, H. Christina Fan, Barry Behr, Stephen.
UvrD Helicase Unwinds DNA One Base Pair at a Time by a Two-Part Power Stroke Jae Young Lee, Wei Yang Cell Volume 127, Issue 7, Pages (December.
Distribution of Human Embryonic Stem Cell Lines: Who, When, and Where Jennifer B. McCormick, Jason Owen-Smith, Christopher Thomas Scott Cell Stem Cell.
Nucleation and Transport Organize Microtubules in Metaphase Spindles Jan Brugués, Valeria Nuzzo, Eric Mazur, Daniel J. Needleman Cell Volume 149, Issue.
Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell
Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome Corinne Ferrier Maurice, Henry Joseph Haiser, Peter James Turnbaugh.
Cancer Metabolism Cell Volume 148, Issue 3, (February 2012) DOI: /j.cell Copyright © 2012 Terms and Conditions Terms and Conditions.
Rpe65 Is the Retinoid Isomerase in Bovine Retinal Pigment Epithelium Minghao Jin, Songhua Li, Walid N. Moghrabi, Hui Sun, Gabriel H. Travis Cell Volume.
The Monarch Butterfly Genome Yields Insights into Long-Distance Migration Shuai Zhan, Christine Merlin, Jeffrey L. Boore, Steven M. Reppert Cell Volume.
Dynein Anchors Its mRNA Cargo after Apical Transport in the Drosophila Blastoderm Embryo Renald Delanoue, Ilan Davis Cell Volume 122, Issue 1, Pages
Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell
Transmembrane Receptor DCC Associates with Protein Synthesis Machinery and Regulates Translation Joseph Tcherkezian, Perry A. Brittis, Franziska Thomas,
The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes Tae-Min Kim, Peter W. Laird, Peter J. Park Cell Volume 155, Issue.
Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.
The Good Fat Cell Volume 147, Issue 7, (December 2011) DOI: /j.cell Copyright © 2011 Terms and Conditions Terms and Conditions.
P120-Catenin Mediates Inflammatory Responses in the Skin Mirna Perez-Moreno, Michael A. Davis, Ellen Wong, H. Amalia Pasolli, Albert B. Reynolds, Elaine.
SRC-3 Coactivator Functional Lifetime Is Regulated by a Phospho-Dependent Ubiquitin Time Clock Ray-Chang Wu, Qin Feng, David M. Lonard, Bert W. O'Malley.
Fate Restriction and Multipotency in Retinal Stem Cells Lázaro Centanin, Burkhard Hoeckendorf, Joachim Wittbrodt Cell Stem Cell Volume 9, Issue 6, Pages.
Stable Kinesin and Dynein Assemblies Drive the Axonal Transport of Mammalian Prion Protein Vesicles Sandra E. Encalada, Lukasz Szpankowski, Chun-hong Xia,
Sensory Detection of Food Rapidly Modulates Arcuate Feeding Circuits Yiming Chen, Yen-Chu Lin, Tzu-Wei Kuo, Zachary A. Knight Cell Volume 160, Issue 5,
Stitching Together Cross-border Research
Volume 168, Issue 4, Pages (February 2017)
Shining a Light on Phase Separation in the Cell
Unweaving the Autism Spectrum
A Blend of Two Circadian Clocks, Seasoned to Perfection
Autophagy: Paying Charon's Toll
Insights into the Neural and Genetic Basis of Vocal Communication
In This Issue Cell Volume 158, Issue 5, (August 2014)
Volume 141, Issue 2, Pages (April 2010)
Jacqueline M. Dresch, David N. Arnosti  Cell Systems 
Stem Cell Therapies: California Dreamin'?
The Importance of Timing
RNA: Jack of All Trades and Master of All
Volume 18, Issue 2, Pages (February 2016)
Imaging the Neural Basis of Locomotion
Should Nurses' Undergraduate Training Be in the Humanities?
Volume 152, Issue 1, (January 2013)
Volume 130, Issue 6, (September 2007)
TensorFlow: Biology’s Gateway to Deep Learning?
Picking Pyknons out of the Human Genome
Volume 143, Issue 6, (December 2010)
Proteins in Plant Brassinosteroid Signaling
Volume 17, Issue 2, Pages (February 1950)
Making the Most from Changes in Life
Both Layers of the COPII Coat Come into View
The Plasticity of Aging: Insights from Long-Lived Mutants
What the Fish’s Eye Tells the Fish’s Brain
Learning from the Uncontrollable
Volume 163, Issue 4, (November 2015)
Immune Cells Exploit a Neural Circuit to Enter the CNS
Volume 163, Issue 2, (October 2015)
Pleckstrin Homology Domains: Two Halves Make a Hole?
Volume 134, Issue 6, (September 2008)
In This Issue Cell Volume 145, Issue 3, (April 2011)
Genomics in Africa: Avoiding Past Pitfalls
Volume 148, Issue 1, (January 2012)
Presentation transcript:

Learning from Everyday Images Enables Expert-like Diagnosis of Retinal Diseases  Ladislav Rampasek, Anna Goldenberg  Cell  Volume 172, Issue 5, Pages 893-895 (February 2018) DOI: 10.1016/j.cell.2018.02.013 Copyright © 2018 Elsevier Inc. Terms and Conditions

Figure 1 Schematic of a Convolutional Neural Network and Transfer Learning Generalizable feature extraction is learned on a loosely related set of tasks but with much larger datasets, such as ImageNet, with 1.2 million images across 1,000 categories. The number of images and variety of classes in the dataset are important for the learning of reusable features. The task-specific data are used to train task-specific upper layers of the neural network and optionally to adjust the copied-over part of the model. The depicted CNN architecture is a simplification of Google’s Inception-v3, Szegedy et al., 2016, where each rectangular component represents a computational layer, e.g., a convolutional or pooling layer. Cell 2018 172, 893-895DOI: (10.1016/j.cell.2018.02.013) Copyright © 2018 Elsevier Inc. Terms and Conditions