(A) Moderately well differentiated adenocarcinoma in subarachnoid space (H&E). (A) Moderately well differentiated adenocarcinoma in subarachnoid space (H&E). Original magnification ×100 (B) Adenocarcinoma in subarachnoid space extending into Virchow- Robins space (H&E). Original magnification ×400 (C) Lumbar spinal cord with leptomeningeal carcinomatosis with dorsal and ventral root infiltration. ×12.5 (cytokeratin 8 immunoperoxidase). Original magnification ×12.5. (D) Lumbar ventral roots showing tumour infiltration (cytokeratin 8 immunoperoxidase). Original magnification ×400. Rebekah M Ahmed et al. Pract Neurol 2013;13:165-173 ©2013 by BMJ Publishing Group Ltd