Volume 4, Issue 6, Pages 548-550 (July 2018) Eosinophilic cellulitis (Wells syndrome) successfully treated with mepolizumab Sandra Herout, MD, Wolfgang Michael Bauer, MD, Christopher Schuster, MD, Georg Stingl, MD JAAD Case Reports Volume 4, Issue 6, Pages 548-550 (July 2018) DOI: 10.1016/j.jdcr.2018.02.011 Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions
Fig 1 Multiple indurated plaques with a central greenish coloration and violaceous borders on the patient's back. JAAD Case Reports 2018 4, 548-550DOI: (10.1016/j.jdcr.2018.02.011) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions
Fig 2 Skin histology findings show superficial and deep perivascular as well as diffuse interstitial infiltration with mostly eosinophilic granulocytes. Arrows point to the presence of so-called flame figures. These flame figures are thought to be cytoplasmic granules released by eosinophils that surround collagen bundles (scale bar = 400 μm). JAAD Case Reports 2018 4, 548-550DOI: (10.1016/j.jdcr.2018.02.011) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions
Fig 3 Two months after initiation of mepolizumab treatment, lesions had healed without scarring. JAAD Case Reports 2018 4, 548-550DOI: (10.1016/j.jdcr.2018.02.011) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions