Pharmacokinetics of Murine p75-Fc Fusion Protein and MP6-XT22 Anti-Murine TNF-α mAb in Mice  Scott G. Filler, Norma V. Solis, Jane Guo, George Doellgast, Ana Ruiz-Garcia, Wei-Jian Pan  Journal of Investigative Dermatology Symposium Proceedings  Volume 12, Issue 1, Pages 52-56 (May 2007) DOI: 10.1038/sj.jidsymp.5650036 Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 Serum concentrations of (a) the MP6-XT22 rat anti-murine TNF-α mAb and (b) the murine p75-Fc protein in mice without infection and in mice with disseminated candidiasis. (a) Mean±SEM of three mice per time point. None of the infected mice survived beyond day 7, precluding comparisons at days 14 and 21. (b) Mean±SEM of 6–7 mice per time point (*P<0.05 using t-test: statistically significant difference between infected and uninfected mice). Journal of Investigative Dermatology Symposium Proceedings 2007 12, 52-56DOI: (10.1038/sj.jidsymp.5650036) Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions