Double GnRH-antagonist dose before HCG administration may prevent OHSS in oocyte-donor cycles: a pilot study  Yannis Prapas, Ioannis Panagiotidis, Ioannis.

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Presentation transcript:

Double GnRH-antagonist dose before HCG administration may prevent OHSS in oocyte-donor cycles: a pilot study  Yannis Prapas, Ioannis Panagiotidis, Ioannis Kalogiannidis, Elinda Gjata, Achileas Papatheodorou, Stella Prapa, Lia Kasapi, Maria Goudakou, Nikos Prapas  Reproductive BioMedicine Online  Volume 21, Issue 2, Pages 159-165 (August 2010) DOI: 10.1016/j.rbmo.2010.04.030 Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

Figure 1 Profile of oestradiol concentrations during the ovarian stimulation and after HCG. A=day 4; B=day 7; C=GnRH antagonist increase; D=day of HCG; E=day of oocyte retrieval; F=day 3 post retrieval. P<0.001: A versus B, A versus C, D versus E and E versus F. P=NS: C versus D and A versus F. Reproductive BioMedicine Online 2010 21, 159-165DOI: (10.1016/j.rbmo.2010.04.030) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

Figure 2 Profile of LH during the ovarian stimulation. A=day 4; B=day 7; C=GnRH antagonist increase; D=day of HCG. P<0.001: A versus B and B versus C. P=0.022: C versus D. Reproductive BioMedicine Online 2010 21, 159-165DOI: (10.1016/j.rbmo.2010.04.030) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions