Volume 1, Issue 5, Pages (September 2015)

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Presentation transcript:

Volume 1, Issue 5, Pages 286-288 (September 2015) Cutaneous adverse drug reaction associated with oral temozolomide presenting as dermal and subcutaneous plaques and nodules Pooja Virmani, MBBS, Esther Chung, BA, Alissa A. Thomas, MD, Ingo K. Mellinghoff, MD, Michael A. Marchetti, MD JAAD Case Reports Volume 1, Issue 5, Pages 286-288 (September 2015) DOI: 10.1016/j.jdcr.2015.06.012 Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Clinical overview image of the legs shows subcutaneous red nodules on the bilateral lower extremities (black arrows). JAAD Case Reports 2015 1, 286-288DOI: (10.1016/j.jdcr.2015.06.012) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Representative photomicrographs of skin biopsies. A, Septal and lobular panniculitis with a mixed cell infiltrate containing numerous eosinophils. B, Dermal mixed cell infiltrate with abundant eosinophils, early flame figures, and edema. (A and B, Hematoxylin-eosin stain; original magnifications: A, ×20; B, ×40.) JAAD Case Reports 2015 1, 286-288DOI: (10.1016/j.jdcr.2015.06.012) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 Clinical overview image shows red plaques and nodules on the back. JAAD Case Reports 2015 1, 286-288DOI: (10.1016/j.jdcr.2015.06.012) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions