Developmental Patterning: Putting the Squeeze on Mis-specified Cells

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Developmental Patterning: Putting the Squeeze on Mis-specified Cells Yu-ichiro Nakajima, Matthew C. Gibson  Current Biology  Volume 26, Issue 5, Pages R204-R206 (March 2016) DOI: 10.1016/j.cub.2016.01.010 Copyright © 2016 Elsevier Ltd Terms and Conditions

Figure 1 Interface contractility between differently fated cells induces cyst formation or single cell elimination depending on clone size. At the interface between cells of different fates (shown as yellow and gray), contractility emerges and becomes a physical force (red arrows). Interface contractility is sufficient for cyst formation in the case of intermediate size clones (A) or leads to the elimination of single cells via apoptosis (B). Magenta, adherens junctions; green, septate junctions; blue, nuclei. Current Biology 2016 26, R204-R206DOI: (10.1016/j.cub.2016.01.010) Copyright © 2016 Elsevier Ltd Terms and Conditions