Volume 83, Issue 4, Pages (April 2013)

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Presentation transcript:

Volume 83, Issue 4, Pages 700-706 (April 2013) Mild hyponatremia is associated with an increased risk of death in an ambulatory setting Fabrice Gankam-Kengne, Colby Ayers, Amit Khera, James de Lemos, Naim M. Maalouf Kidney International Volume 83, Issue 4, Pages 700-706 (April 2013) DOI: 10.1038/ki.2012.459 Copyright © 2013 International Society of Nephrology Terms and Conditions

Figure 1 Kaplan–Meier cumulative hazard curves for mortality for patients with and without hyponatremia. Kidney International 2013 83, 700-706DOI: (10.1038/ki.2012.459) Copyright © 2013 International Society of Nephrology Terms and Conditions

Figure 2 Spline curve of hazard ratio for overall mortality according to the baseline serum sodium (corrected for glucose). (a) Unadjusted hazard ratio. (b) Adjusted hazard ratio. Kidney International 2013 83, 700-706DOI: (10.1038/ki.2012.459) Copyright © 2013 International Society of Nephrology Terms and Conditions

Figure 3 Unadjusted hazard ratio (HR) for mortality in the whole population and selected subgroups. CHF, congestive heart failure; eGFR, estimated glomerular filtration rate. Comorbidities include presence of cirrhosis, CHF, cancer, eGFR <60ml/min per 1.73m2, or use of diuretics. The P-value for interaction was >0.05 in all subgroups studied. Kidney International 2013 83, 700-706DOI: (10.1038/ki.2012.459) Copyright © 2013 International Society of Nephrology Terms and Conditions