Nuclear Decay Factors Crack Up mRNA

Slides:



Advertisements
Similar presentations
Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester Transfer Shaun K. Olsen, Christopher D. Lima Molecular Cell Volume 49, Issue 5, Pages.
Advertisements

HnRNP L and HnRNP A1 Induce Extended U1 snRNA Interactions with an Exon to Repress Spliceosome Assembly Ni-Ting Chiou, Ganesh Shankarling, Kristen W. Lynch.
Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.
An Ancient Mechanism for Splicing Control: U11 snRNP as an Activator of Alternative Splicing Jens Verbeeren, Elina H. Niemelä, Janne J. Turunen, Cindy.
Cost of Unneeded Proteins in E. coli Is Reduced after Several Generations in Exponential Growth Irit Shachrai, Alon Zaslaver, Uri Alon, Erez Dekel Molecular.
Telomeric Noncoding RNA TERRA Is Induced by Telomere Shortening to Nucleate Telomerase Molecules at Short Telomeres Emilio Cusanelli, Carmina Angelica.
Molecular Basis for Coordinating Transcription Termination with Noncoding RNA Degradation Agnieszka Tudek, Odil Porrua, Tomasz Kabzinski, Michael Lidschreiber,
Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem
Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell
The BCL-2 Family Reunion Jerry E. Chipuk, Tudor Moldoveanu, Fabien Llambi, Melissa J. Parsons, Douglas R. Green Molecular Cell Volume 37, Issue 3, Pages.
The Mitochondrial Basis of Aging Nuo Sun, Richard J. Youle, Toren Finkel Molecular Cell Volume 61, Issue 5, Pages (March 2016) DOI: /j.molcel
Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel
Sex-Specific Aging in Flies, Worms, and Missing Great-Granddads
Untangling P-Bodies: Dissecting the Complex Web of Interactions that Enable Tiered Control of Gene Expression  Christopher J. Kershaw, Mark P. Ashe  Molecular.
UneCLIPsing HuR Nuclear Function
Central Dogma Goes Digital
Volume 47, Issue 1, Pages (July 2012)
Stopping the Clock with MYC
RNase E Finds Some sRNAs Stimulating
p53 and Apoptosis: It's Not Just in the Nucleus Anymore
Kai Papenfort, Jörg Vogel  Molecular Cell 
Haunting the HOXA Locus: Two Faces of lncRNA Regulation
Methed-Up FOXOs Can't In-Akt-ivate
Skill Development in Graduate Education
A Pause to Splice Molecular Cell
Akos A. Gerencser, Martin D. Brand  Molecular Cell 
PU.1 Takes Control of the Dendritic Cell Lineage
How To Choose a Good Scientific Problem
A New Link in the Chain from Amino Acids to mTORC1 Activation
P Bodies and the Control of mRNA Translation and Degradation
Jan Philipp Junker, Alexander van Oudenaarden  Molecular Cell 
Utf1: Goldilocks for ESC Bivalency
RNA-Seeded Functional Amyloids Balance Growth and Survival
Wilma Ziebuhr, Jörg Vogel  Molecular Cell 
Karin Johanna Ferrari, Elisa Lavarone, Diego Pasini  Molecular Cell 
The Importance of Timing
From Protein-RNA Predictions toward a Peptide-RNA Code
Arven Saunders, Jianlong Wang  Cell Stem Cell 
HMGA2, MicroRNAs, and Stem Cell Aging
Joseph W. Briggs, Jonathan D. Dinman  Molecular Cell 
PAF Makes It EZ(H2) for β-Catenin Transactivation
William G. Kaelin, Peter J. Ratcliffe  Molecular Cell 
Eukaryotic Transcription Activation: Right on Target
Anne F. Nielsen, Jiradet Gloggnitzer, Javier Martinez  Molecular Cell 
Joseph W. Briggs, Jonathan D. Dinman  Molecular Cell 
An Argonaute Protein Directs Nuclear Xrn2 Function
Untangling P-Bodies: Dissecting the Complex Web of Interactions that Enable Tiered Control of Gene Expression  Christopher J. Kershaw, Mark P. Ashe  Molecular.
Activating and Repressing IRE1α: The Hsp47 and BiP Tug of War
Small Molecules, Big Effects: A Role for Chromatin-Localized Metabolite Biosynthesis in Gene Regulation  Bryan A. Gibson, W. Lee Kraus  Molecular Cell 
A Method that Will Captivate U
Phytochromes: Where to Start?
Arina D. Omer, Maja M. Janas, Carl D. Novina  Molecular Cell 
Dealing with Pervasive Transcription
Transferring Death: A Role for tRNA in Apoptosis Regulation
Competition by the Masses
Volume 49, Issue 1, Pages 1-3 (January 2013)
Proteins in Plant Brassinosteroid Signaling
Long Noncoding RNAs Add Another Layer to Pre-mRNA Splicing Regulation
Functional Enhancer Screening in Single Cells
Chromatin Dynamics and Gene Positioning
Antiviral Immunity and Circular RNA: No End in Sight
Exercise Controls Non-Coding RNAs
Molecular Mechanisms of Long Noncoding RNAs
Molecular Therapy  Volume 18, Pages S260-S261 (May 2010) DOI: /S (16)
How To Choose a Good Scientific Problem
Volume 61, Issue 2, Pages (January 2016)
Volume 24, Issue 1, Pages 7-8 (July 2016)
The Aging Epigenome Molecular Cell
Gene Regulation in the Postgenomic Era: Technology Takes the Wheel
RNA Processing: Redrawing the Map of Charted Territory
Presentation transcript:

Nuclear Decay Factors Crack Up mRNA Agnieszka Tudek, Manfred Schmid, Torben Heick Jensen  Molecular Cell  Volume 65, Issue 5, Pages 775-776 (March 2017) DOI: 10.1016/j.molcel.2017.02.014 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 Nuclear RNA Decay Factors Aid Reprogramming of Gene Expression Regulated steps during reprogramming of gene expression (left). Bresson et al. (2017) find relatively increased binding of NNS and TRAMP complexes to mRNA from transcriptionally repressed genes, which may lead to nuclear RNA decay and reciprocally decreased binding to mRNA from transcriptionally induced genes (right). See text for details. Molecular Cell 2017 65, 775-776DOI: (10.1016/j.molcel.2017.02.014) Copyright © 2017 Elsevier Inc. Terms and Conditions