Standard Annotation Presentation

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Standard Annotation Presentation Robert Kalish

Annotation Protein: Staphylococcus Phage g1 gp67 Uniprot id: 9caud:q4z9y5 The authors tested the effect of staphylococcus phage G1 gp67 on transcription in the bacteria Staphylococcus aureus. In figure 1 of the paper linked, it is shown that the addition of the protein gp67 inhibits the transcription of RNA in Staphylococcus aureus.

Figure 1 Fig 1 shows the reduction of transcription catalyzed by the Sau RNAP Holoenzyme found in Staph aureus as Gp67 levels increase.

Figure 2 In Figure 2 pictured above, Darst et al. observed the effect Gp67 on Staph aureus. Although the levels of previously transcribed RNA were unchanged, it greatly diminished transcription of new RNA labeled with 32P.

ID numbers and Transfer Annotations GO:0039602 - suppression by virus of host transcription initiation from RNA polymerase II promoter (P) Pubmed ID: 23178120 Evidence: IDA Transfer annotations found through over 75% Blastp identity and query: 9CAUD:K7QMU4  Staph Phage JD007 gp 213 9CAUD:I6PCI8  Staph Phage Gh15 gp 128 9CAUD:A0A076YNB0  Staph Phage P108 gp028 ISS and GO_REF:0000100 used as evidence