Boxuan Simen Zhao, Chuan He Molecular Cell

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“Gamete On” for m6A: YTHDF2 Exerts Essential Functions in Female Fertility Boxuan Simen Zhao, Chuan He Molecular Cell Volume 67, Issue 6, Pages 903-905 (September 2017) DOI: 10.1016/j.molcel.2017.09.004 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 The Picky YTHDF2 As one of the primary m6A readers in the cytoplasm, YTHDF2 promotes mRNA degradation and facilitates transcriptome switching. It targets a specific cohort of mRNA transcripts and functions during defined stages of several biological processes, including murine oocyte maturation (and possibly early zygotic development, shown by dotted line) and zebrafish maternal-to-zygotic transition during embryogenesis. Molecular Cell 2017 67, 903-905DOI: (10.1016/j.molcel.2017.09.004) Copyright © 2017 Elsevier Inc. Terms and Conditions