Association of myeloperoxidase with total and cardiovascular mortality in individuals undergoing coronary angiography—The LURIC study Hubert Scharnagl,

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Association of myeloperoxidase with total and cardiovascular mortality in individuals undergoing coronary angiography—The LURIC study Hubert Scharnagl, Marcus E. Kleber, Bernd Genser, Sandra Kickmaier, Wilfried Renner, Gisela Weihrauch, Tanja Grammer, Christine Rossmann, Bernhard R. Winkelmann, Bernhard O. Boehm, Wolfgang Sattler, Winfried März, Ernst Malle International Journal of Cardiology Volume 174, Issue 1, Pages 96-105 (June 2014) DOI: 10.1016/j.ijcard.2014.03.168 Copyright © 2014 The Authors Terms and Conditions

Fig. 1 Association of MPO quartiles with markers of inflammation and vascular damage. MPO plasma concentrations were stratified into quartiles; values represent estimated marginal means and 95% confidence intervals obtained in a general linear model (ANOVA), adjusted for the use of lipid-lowering drugs and for each of the other factors, whereby age, body mass index, LDL-C, HDL-C, and triglycerides (log transformed), were included as continuous rather than categorial co-variables. Significance is indicated by *(P<0.05), **(P<0.01), and ***(P<0.001) compared to the first MPO quartile. (Interleukin-6, IL-6; C-reactive protein, CRP; serum amyloid A, SAA; vascular cellular adhesion molecule-1, VCAM-1; intercellular adhesion molecule-1, ICAM-1). International Journal of Cardiology 2014 174, 96-105DOI: (10.1016/j.ijcard.2014.03.168) Copyright © 2014 The Authors Terms and Conditions

Fig. 2 Cumulated survival functions for all cause and cardiovascular mortality. Cumulated survival functions for total (top panels) and cardiovascular mortality (bottom panels) according to quartiles (Q1–Q4) of MPO in all individuals (left panels) or in patients with angiographic CAD (right panels). Curves were estimated using a proportional hazard model adjusted for age, gender and cardiovascular risk factors. For HRs and confidence intervals, see Tables 4 and 5 (Model 3). International Journal of Cardiology 2014 174, 96-105DOI: (10.1016/j.ijcard.2014.03.168) Copyright © 2014 The Authors Terms and Conditions