*****For more information, please call***** BIOMARKER STUDY FOR TREATMENT RESPONSE in DEPRESSION Feeling depressed or have been diagnosed with depression? The aim of this study is to identify brain, cognitive and genetic markers that predict treatment response to 3 antidepressant medications. This study is for male or female individuals who are: 18-65 years of age Diagnosed with major depressive disorder and no recent use of antidepressant medication Whose primary language is English You will be required to satisfy study criteria and attend a medical screening and clinical assessment before being permitted to participate in the study. While your brain activity is being measured via non-invasive brain-mapping methods, you will be asked to perform various tasks (e.g. focused attention, memory recall, etc.). You will also be asked to provide a blood sample, and answer questions about your medical history. The study will involve two 5-6 hour testing sessions and additional 30 minute phone and internet follow-up sessions. You will be compensated for your time and any costs incurred in participating in this study. *****For more information, please call***** Brain Resource Center at: 212-877-0424 or email: ispot@brain-resource.com Or visit our website at www.brain-resource.com