Volume 20, Issue 3, Pages (June 2013)

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Volume 20, Issue 3, Pages 181-189 (June 2013) Does CA1 dopaminergic system play a role in cholestasis induced hypothermia?  Mohammad Nasehi, Omar Ahmadzadeh, Ameneh Rezayof, Mohammad-Reza Zarrindast  Pathophysiology  Volume 20, Issue 3, Pages 181-189 (June 2013) DOI: 10.1016/j.pathophys.2013.08.004 Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 (A) The location of the injection-cannulae tip in the CA1 regions for all mice included in the data analyses. (B) Verified section of CA1 was taken from the Mouse Brain in Stereotaxic Coordinates Paxinos [17]. Pathophysiology 2013 20, 181-189DOI: (10.1016/j.pathophys.2013.08.004) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 The time course effect of BDL on body temperature. Three groups of animals, i.e. non-operated, sham-operated and BDL, were used. The animals’ body temperatures were measured zero, two, four, six and eight days following BDL. The plots are expressed as mean±S.E.M. *P<0.05 and ***P<0.001 when compared to the respective groups. Pathophysiology 2013 20, 181-189DOI: (10.1016/j.pathophys.2013.08.004) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

Fig. 3 The effects of SCH on BDL induced hypothermia. Different doses of SCH or saline were injected in non-operated, sham-operated and BDL mice and body temperatures were recorded zero, two and four days following BDL. The plots are expressed as mean±S.E.M. *P<0.05 and **P<0.01 when compared to the day zero measurements in the control group. Pathophysiology 2013 20, 181-189DOI: (10.1016/j.pathophys.2013.08.004) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

Fig. 4 The effects of SKF on BDL induced hypothermia. Different doses of SKF or saline were injected in non-operated, sham-operated and BDL mice and body temperatures were measured zero, two and four days following BDL. The plots are expressed as mean±S.E.M. **P<0.01 and ***P<0.001 when compared to the day zero measurements in the control group. +P<0.05 and +++P<0.001 when compared to the respective control groups. Pathophysiology 2013 20, 181-189DOI: (10.1016/j.pathophys.2013.08.004) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

Fig. 5 The effects of SUL on BDL induced hypothermia. Different doses of SUL, vehicle or saline were injected in non-operated, sham-operated and BDL mice and body temperatures were recorded zero, two and four days after BDL. The plots are expressed as mean±S.E.M. *P<0.05 and **P<0.01 when compared to the day zero measurements in the control group. ++P<0.01 when compared to the respective control groups. Pathophysiology 2013 20, 181-189DOI: (10.1016/j.pathophys.2013.08.004) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

Fig. 6 The effects of QUI on BDL induced hypothermia. Different doses of QUI or saline were injected in non-operated, sham-operated and BDL mice and body temperatures were measured zero, two and four days following BDL. The plots are expressed as mean±S.E.M. **P<0.01 and ***P<0.001 when compared to the day zero measurements in the control group. +P<0.05 and ++P<0.01 when compared to the respective control groups. Pathophysiology 2013 20, 181-189DOI: (10.1016/j.pathophys.2013.08.004) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions