Skip Mediastinal Nodal Metastases in the IIIa/N2 Non-Small Cell Lung Cancer Nenad Ilic, MD, PhD, Ante Petricevic, MD, PhD, Dragan Arar, MD, Slavica Kotarac,

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Skip Mediastinal Nodal Metastases in the IIIa/N2 Non-Small Cell Lung Cancer Nenad Ilic, MD, PhD, Ante Petricevic, MD, PhD, Dragan Arar, MD, Slavica Kotarac, MD, PhD, Josip Banovic, MD, Nives Frleta Ilic, MD, Andro Tripkovic, MD, Leo Grandic, MD Journal of Thoracic Oncology Volume 2, Issue 11, Pages 1018-1021 (November 2007) DOI: 10.1097/JTO.0b013e318158d471 Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Columns represent percent of each histologic non-small cell lung cancer subtype within total IIIA/N2 stage population. Each column has two different parts, depending on skip metastases presence. Note that skip N2+ subgroup represents almost 50% of N2+ squamous cell lung cancer population. Adenoca, adenocarcinoma. Journal of Thoracic Oncology 2007 2, 1018-1021DOI: (10.1097/JTO.0b013e318158d471) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Five-year survival rates after surgery according to N status. The fourth and the fifth years of follow-up refer only to one third of the patients because the other two thirds survived to 3-year follow-up. Differences in survival rates for N0, N1, and N2 groups are statistically significant (p < 0.05). Journal of Thoracic Oncology 2007 2, 1018-1021DOI: (10.1097/JTO.0b013e318158d471) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 Five years after surgery, the survival of the different pN2+ subgroups is shown. Although one-level skip pN2+ is a subgroup of the N2 group with a better prognosis, differences in survival rates for one-level skip N2+, multilevel skip N2+, and N2+ (N1+) groups are not statistically significant (p > 0.05). Journal of Thoracic Oncology 2007 2, 1018-1021DOI: (10.1097/JTO.0b013e318158d471) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions