Volume 18, Issue 4, Pages 273-278 (September 2011) Vascular mechanisms of cyanidin-3-glucoside response in streptozotocin-diabetic rats  Sima Nasri, Mehrdad Roghani, Tourandokht Baluchnejadmojarad, Tahereh Rabani, Mahboubeh Balvardi  Pathophysiology  Volume 18, Issue 4, Pages 273-278 (September 2011) DOI: 10.1016/j.pathophys.2011.03.001 Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Body weight and serum glucose concentration in STZ diabetic and control rat groups treated by C3G (cyanidin) and glibenclamide 0, 4 or 8 weeks (means±SEM). *p<0.05, **p<0.01, ***p<0.001 (as compared to week 0 in the same group); #p<0.05, ##p<0.01, ###p<0.005 (as compared to diabetics in the same week). Pathophysiology 2011 18, 273-278DOI: (10.1016/j.pathophys.2011.03.001) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 Cumulative concentration–response curves for KCl and PE in preparations of rat aortas after 8 weeks treatment (see Fig. 1 for explanations) in the presence (A) and absence (B) of endothelium (means±SEM). **p<0.01 (as compared to control); φp<0.05 (as compared to diabetic), §p<0.05 (as compared to control). Pathophysiology 2011 18, 273-278DOI: (10.1016/j.pathophys.2011.03.001) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

Fig. 3 Cumulative concentration-response curves for ACh in rat aortic rings precontracted with PE after 8 weeks treatments (see Fig. 1 for explanations). Relaxation responses have been expressed as percentages. *p<0.05, **p<0.01 (as compared to control); φp<0.05 (as compared to diabetic), §p<0.05 (as compared to control). Pathophysiology 2011 18, 273-278DOI: (10.1016/j.pathophys.2011.03.001) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

Fig. 4 MDA concentrations in aorta homogenate supernatant from different rat groups treated for 8 weeks (see Fig. 1 for explanations). *p<0.05, **p<0.01 (in comparison with control). #p<0.05 (in comparison with diabetic). Pathophysiology 2011 18, 273-278DOI: (10.1016/j.pathophys.2011.03.001) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

Fig. 5 Superoxide dismutase (SOD) activity in aorta homogenate supernatant from different rat groups. (see Fig. 1 for explanations). *p<0.05 (in comparison with control). Pathophysiology 2011 18, 273-278DOI: (10.1016/j.pathophys.2011.03.001) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions