Investigate the Treatment of Infectious Diseases

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Presentation transcript:

Investigate the Treatment of Infectious Diseases Drugs used in treatment of infectious diseases BT06.03

Drugs used for treatment of bacterial diseases Drugs used for treatment of bacterial diseases can be grouped into categories based on their modes of action Examples: Penicillins/Cephalosporins interfere with certain layers of the cell wall Chloramphenicol Tetracyclines, Erythromycins-may be toxic when used in high doses or prolonged periods of time Rifampin-used for treatment of TB

Drugs that Inhibit Viral Infections Drugs that effectively inhibit viral infections are highly toxic to host cells because viruses use the host’s metabolic enzymes in reproduction Examples: Antiviral drugs target virus-specific enzymes ACYCLOVIR-used in treatment of genital herpes AMANTIDINE (Tamiflu)-used to prevent or moderate influenza AZT-inhibit replication of HIV genome

Development of Drugs Development of drugs used to treat fungal, protozoan & helminthic disease are also highly toxic to mammals Examples: Azole derivatives inhibit sterol synthesis Amphotericin B-disrupts cell membrane

Antimicrobial Resistance Antimicrobial resistance presents ongoing problems in the fight against infectious disease Penicillin resistance noted as early as 1943 Mycobacterium tuberculosis-some strains resistant to all drugs Resistance to antibiotics-result of changes in genetic information [MUTATIONS]

Using the rain forest to fight viruses?? http://www.healingseekers.com/wxii-news-triad-woman-uses-rainforest-to-fight-viruses/