Sorafenib As Monotherapy or in Association With Cytarabine and Clofarabine for the Treatment of Relapsed/Refractory FLT3 ITD-Positive Advanced Acute Myeloid.

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Sorafenib As Monotherapy or in Association With Cytarabine and Clofarabine for the Treatment of Relapsed/Refractory FLT3 ITD-Positive Advanced Acute Myeloid Leukemia  Giulia Fontanelli, Melania Rocco, Francesco Caracciolo, Edoardo Benedetti, Gabriele Buda, Enrico Orciuolo, Giovanni Carulli, Sara Galimberti, Antonio Azzarà, Mario Petrini  Clinical Lymphoma, Myeloma and Leukemia  Volume 14, Issue 1, Pages e13-e17 (February 2014) DOI: 10.1016/j.clml.2013.08.005 Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 1 FLT3 ITD Mutation in Patient 2. (A) Before Sorafenib Treatment; (B) After Sorafenib Treatment. The Peak at 428 Represents the Wild Type FLT3; the Peak at 437 Represents the ITD Allele Abbreviations: bp = base pair; FLT = fms-related tyrosine kinase; ITD = internal tandem duplication. Clinical Lymphoma, Myeloma and Leukemia 2014 14, e13-e17DOI: (10.1016/j.clml.2013.08.005) Copyright © 2014 Elsevier Inc. Terms and Conditions

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