Persistent Hyperammonemia Is Associated With Complications and Poor Outcomes in Patients With Acute Liver Failure  Ramesh Kumar, Shalimar, Hanish Sharma, Shyam Prakash, Subrat Kumar Panda, Shankar Khanal, Subrat Kumar Acharya  Clinical Gastroenterology and Hepatology  Volume 10, Issue 8, Pages 925-931 (August 2012) DOI: 10.1016/j.cgh.2012.04.011 Copyright © 2012 AGA Institute Terms and Conditions

Figure 1 Kaplan–Meier plots showing 2-week survival (%) in ALF patients stratified according to severity of baseline ammonia (levels ≥122 and <122 μmol/L, A) or persistent hyperammonemia; (B) persistent levels ≥122 μmol/L for 3 days (subgroup A), and declining levels to <122 μmol/L by 3 days (subgroup B); and (C) persistent levels ≥85 μmol/L for 3 days (subgroup C), and low declining levels <85 μmol/L for 3 days (subgroup D). Clinical Gastroenterology and Hepatology 2012 10, 925-931DOI: (10.1016/j.cgh.2012.04.011) Copyright © 2012 AGA Institute Terms and Conditions

Figure 2 Serial arterial ammonia levels in patients with CE at presentation (A, n = 116) or without CE at presentation (B, n = 179). Serial ammonia levels in patients presenting with early HE (C, n = 81) and advanced HE (D, n = 214). Serial arterial ammonia levels in patients with or without documented infection (E). Clinical Gastroenterology and Hepatology 2012 10, 925-931DOI: (10.1016/j.cgh.2012.04.011) Copyright © 2012 AGA Institute Terms and Conditions