Ching-wen Cheng, Ph. D. , Stephen K. Smith, M. D. , D

Slides:

Advertisements

Similar presentations

TAGLN expression is deregulated in endometriosis and may be involved in cell invasion, migration, and differentiation Gabriela dos Santos Hidalgo, M.Sc.,

Advertisements

Sphingosine pathway deregulation in endometriotic tissues

Sachiko Matsuzaki, M. D. , Takashi Murakami, M. D. , Shigeki Uehara, M

Genome-based expression profiling as a single standardized microarray platform for the diagnosis of endometrial disorder: an array of 126-gene model

Increased expression of c-fos protein associated with increased matrix metalloproteinase-9 protein expression in the endometrium of endometriotic patients

Increased expression of macrophage colony–stimulating factor and its receptor in patients with endometriosis Nicole M. Budrys, M.D., M.P.H., Hareesh.

Thyroid-stimulating hormone receptor and thyroid hormone receptors are involved in human endometrial physiology Lusine Aghajanova, M.D., Ph.D., Anneli.

The relative effects of hormones and relationship factors on sexual function of women through the natural menopausal transition Lorraine Dennerstein,

Eutopic endometrial interleukin-18 system mRNA and protein expression at the level of endometrial-myometrial interface in adenomyosis patients Hong-Yuan.

Glycodelin A is expressed differentially in normal human endometrial tissue throughout the menstrual cycle as assessed by immunohistochemistry and in.

Sébastien Colette, Ph. D. , Sylvie Defrère, Ph. D

TAGLN expression is deregulated in endometriosis and may be involved in cell invasion, migration, and differentiation Gabriela dos Santos Hidalgo, M.Sc.,

Growth rates of ovarian follicles during natural menstrual cycles, oral contraception cycles, and ovarian stimulation cycles Angela R. Baerwald, Ph.D.,

Expression of motility-related molecule Cdc42 in endometrial tissue in women with adenomyosis and ovarian endometriomata Gaia Goteri, M.D., Andrea Ciavattini,

The expression of estrogen receptors as well as GREB1, c-MYC, and cyclin D1, estrogen-regulated genes implicated in proliferation, is increased in peritoneal.

Expression of microtubule associated protein 2 and synaptophysin in endometrium: high levels in deep infiltrating endometriosis lesions Martina Gori,

Aldo Cavallini, B. Sc. , Leonardo Resta, M. D

Increased expression of p21-activated kinase in adenomyosis

Regine Gaetje, M. D. , Uwe Holtrich, Ph. D. , Thomas Karn, Ph. D

Endometrial stromal progesterone receptor-A/progesterone receptor-B ratio: no difference between women with and without endometriosis Davide Gentilini,

Regulation of myeloid ecotropic viral integration site 1 and its expression in normal and abnormal endometrium Linli Hu, M.D., Haixia Li, M.D., CindyTzu-Ling.

Interleukin-18 system messenger RNA and protein expression in human endometrium during the menstrual cycle Hong-Yuan Huang, M.D., She-Hung Chan, B.Sc.,

A potential role for colony-stimulating factor 1 in the genesis of the early endometriotic lesion Jani R. Jensen, M.D., Craig A. Witz, M.D., Robert S.

Vascular density and distribution of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 (Flk-1) are significantly higher in patients with.

Sana M. Salih, M. D. , Salama A. Salama, Ph. D. , Amin A. Fadl, Ph. D

Increased matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 secretion but unaffected invasiveness of endometrial stromal cells in.

Genome-based expression profiling as a single standardized microarray platform for the diagnosis of endometrial disorder: an array of 126-gene model

Immunohistochemical detection of aquaporin expression in eutopic and ectopic endometria from women with endometriomas Xiu-Xiu Jiang, M.D., Riu-Jin Wu,

Lusine Aghajanova, M. D. , Ph. D. , Signe Altmäe, Ph. D

Pathophysiologic features of “thin” endometrium

Kathryn Smith, M. D. , Redab Alnifaidy, Qingxiang Wei, M. A

Xiao-Yu Pan, Ph. D. , Xue Li, M. D. , Zhan-Ping Weng, Ph. D

Up-regulation of p21-activated kinase 1 by in vitro treatment with interleukin 1-beta and its increased expression in ovarian endometriotic cysts Mi.

Endometrial LGR7 expression during menstrual cycle

Immunohistochemical detection of heparanase-1 expression in eutopic and ectopic endometrium from women with endometriosis Xiulong Xu, Ph.D., Jianchi.

Up-regulation of endocrine gland-derived vascular endothelial growth factor but not vascular endothelial growth factor in human ectopic endometriotic.

Mu opioid receptor in the human endometrium: dynamics of its expression and localization during the menstrual cycle Lide Totorikaguena, B.S., Estibaliz.

Tamir S. Aldad, B. A. , Nora Rahmani, B. A. , Csaba Leranth, Ph. D

Prokineticin 1, homeobox A10, and progesterone receptor messenger ribonucleic acid expression in primary cultures of endometrial stromal cells isolated.

Deoxyribonucleic acid methyltransferases and methyl-CpG-binding domain proteins in human endometrium and endometriosis Kim J.A.F. van Kaam, M.D., Bert.

Protein profiling of human endometrial tissues in the midsecretory and proliferative phases of the menstrual cycle Tanu Parmar, M.S., Sushama Gadkar-Sable,

Murat Ulukus, M. D. , E. Cagnur Ulukus, M. D. , Ege N

Lipidomics as an emerging tool to predict endometrial receptivity

Nina Chehna-Patel, M. Sc. , Geetanjali Sachdeva, Ph. D

Putative stem cell activity of human endometrial epithelial and stromal cells during the menstrual cycle Kjiana Elkje Schwab, B.Biomed.Sci. (Hons.),

Macrophage migration inhibitory factor expression in the intrauterine endometrium of women with endometriosis varies with disease stage, infertility status,

Management of tubal ectopic pregnancy: methotrexate and salpingostomy are preferred to preserve fertility Stephanie Beall, M.D., Ph.D., Alan H. DeCherney,

Christophe Poncelet, M. D. , Ph. D. , Françoise Cornelis, M. D

Aromatase expression in abdominal omental/visceral and subcutaneous fat depots: a comparison of pregnant and obese women Suman Rice, Ph.D., Bijal Patel,

Qiong-Hua Chen, Ph. D. , Wei-Dong Zhou, Ph. D. , De-Min Pu, M. D

Reduced expression of progesterone receptor-B in the endometrium of women with endometriosis and in cocultures of endometrial cells exposed to 2,3,7,8-

Ana Luiza L. Rocha, M. D. , Patrizia Carrarelli, B. Sc

Letrozole stimulates the growth of human endometrial explants cultured in three- dimensional fibrin matrix Mozafar Khazaei, Ph.D., Azadeh Montaseri, M.Sc.,

Laura Detti, M. D. , Rebecca A. Uhlmann, M. S. , Nicole M. Fletcher, B

Fei Wang, M. D. , Ph. D. , Zeqing Wen, M. D. , Hui Li, Ph. D

Physiologic activation of nuclear factor kappa-B in the endometrium during the menstrual cycle is altered in endometriosis patients Reinaldo González-Ramos,

CDB-2914, a novel selective progesterone receptor modulator, differentially regulates endometrial gene expression in the proliferative phase of the menstrual.

Jui-Hung Chang, Ph. D. , Heng-Kien Au, M. D. , Wei-Chin Lee, M. S

Lin Mu, Ph. D. , Wei Zheng, Ph. D. , M. D. , Liang Wang, Ph. D

Prokineticin 1 mRNA expression in the endometrium of healthy women and in the eutopic endometrium of women with endometriosis Federica Tiberi, B.S.,

Elevated levels of gremlin-1 in eutopic endometrium and peripheral serum in patients with endometriosis Guihua Sha, Ph.D., Yan Zhang, M.D., Chengyan.

Expression of leucine-rich repeat-containing G-protein-coupled receptors in the human cyclic endometrium Claudia A. Krusche, Ph.D., Tina Kroll, Henning.

Differences in gene expression in the proliferative human endometrium

Quantitative expression of apoptosis-regulating genes in endometrium from women with and without endometriosis Donald P. Braun, Ph.D., Jianchi Ding,

Nerve fibers and menstrual cycle in peritoneal endometriosis

A selective cyclooxygenase-2 inhibitor suppresses the growth of endometriosis with an antiangiogenic effect in a rat model Daniel Escorsim Machado, M.Sc.,

An epigenetic disorder may cause aberrant expression of aromatase gene in endometriotic stromal cells Masao Izawa, Ph.D., Tasuku Harada, M.D., Fuminori.

Patrizia Carrarelli, M. Sc. , Ana Luiza Lunardi Rocha, M. D

Expression of leukemia inhibitory factor in the endometrium in abnormal uterine cavities during the implantation window Ei Hasegawa, M.D., Hiroe Ito,

Moamar Al-Jefout, M. D. , Kirsten Black, M. D. , Lauren Schulke, M. Sc

Presentation transcript:

Transcript profile and localization of Wnt signaling–related molecules in human endometrium Ching-wen Cheng, Ph.D., Stephen K. Smith, M.D., D. Stephen Charnock-Jones, Ph.D. Fertility and Sterility Volume 90, Issue 1, Pages 201-204 (July 2008) DOI: 10.1016/j.fertnstert.2007.05.077 Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 1 (a) Cellular localization of SFRP1 mRNA detected by in situ hubridization in endometrium. Column 1 (A, C, E, and G) represents the dark-field images during proliferative, secretory, menstrual phase endometrium, and sense probe control, respectively; column 2 (B, D, F, and H) represents the corresponding bright-field images. Signals for SFRP1 mRNA are detectable in all phases of endometrium and are positive in overall endometrium. However, signals are stronger in stromal area compared with glands and vessels. Note that there are signal clusters on some cells in menstrual phase endometrium. Column 3 (I and J) shows higher-magnification pictures of menstrual phase endometrium, and arrows indicate signal clusters. (b) Relative levels of SFRP1 mRNA in endometrium throughout the menstrual cycle. Quantitative PCR reactions were preformed using human endometrial tissue (n = 2) from seven different phases (n = 2). Each spot represents the relative SFRP1 mRNA level of one tissue sample. SFRP1 mRNA is detectable in all phases of human endometrium throughout the menstrual cycle. However, relative level of SFRP1 mRNA is significantly higher in proliferative-phase endometrium (Mann-Whitney test, P<.01). (c) Relative levels of SFRP1 mRNA in human endometriotic tissue (n = 6) and eutopic endometrium (n = 6). Each spot represents the relative SFRP1 mRNA level in one tissue sample. Relative level of SFRP1 mRNAs is significantly higher in ectopic tissues than in eutopic tissues (Mann-Whitney test, P<.01). Fertility and Sterility 2008 90, 201-204DOI: (10.1016/j.fertnstert.2007.05.077) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions