Mohanraj K. Karunanithi, BE, MBiomedE, Michael P

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Presentation transcript:

Limitations of unidimensional indexes of right ventricular contractile function in conscious dogs Mohanraj K. Karunanithi, BE, MBiomedE, Michael P. Feneley, MD, FRACP, FACC The Journal of Thoracic and Cardiovascular Surgery Volume 120, Issue 2, Pages 302-312 (August 2000) DOI: 10.1067/mtc.2000.105828 Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

Fig. 1 Representative pressure-volume and pressure-dimension loops obtained from 1 dog during a single vena caval occlusion (upper panels) and the corresponding global and unidimensional PRSW relationships derived from these loops (lower panels). EDV, EDD, and EDL, End-diastolic volume, dimension, and length; RV, right ventricular; SWG, SWD, and SWL, global, dimensional and segmental stroke work; MwG, MwD, and MwL, global, septal–free wall dimensional and free wall segmental PRSW slopes; Vw, Dw, and Lw, global, dimensional and segmental PRSW x-axis intercepts. The Journal of Thoracic and Cardiovascular Surgery 2000 120, 302-312DOI: (10.1067/mtc.2000.105828) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

Fig. 2 Representative recordings of cardiac dimensions and RV and LV pressure from 1 dog before and during aortic constriction and pulmonary arterial constriction, the onsets of which are indicated by the arrows. RV, Right ventricular; LV, left ventricular. The Journal of Thoracic and Cardiovascular Surgery 2000 120, 302-312DOI: (10.1067/mtc.2000.105828) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

Fig. 3 Relationships between unidimensional and global RV hemodynamic variables derived from vena caval occlusions performed before (control) and during pulmonary arterial constriction (PAC) or aortic constriction (AC). End-diastolic and end-systolic data were normalized to the steady-state value under control conditions. EDV, EDD, and EDL, End-diastolic volume, dimension, and length; ESV, ESD, and ESL, end-systolic volume, dimension, and length; SV, stroke volume; SWG, SWD, and SWL, global, dimensional, and segmental stroke work. The Journal of Thoracic and Cardiovascular Surgery 2000 120, 302-312DOI: (10.1067/mtc.2000.105828) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

Fig. 4 Examples of global and unidimensional PRSW relationships obtained under control conditions and during pulmonary arterial constriction (PAC) and aortic constriction (AC) for the dogs with the best (upper panels) and worst (middle panels) linear correlations. The lower panels represent the results of regression analyses of the pooled data from all dogs. EDV, EDD, and EDL, End-diastolic volume, dimension, and length; SWG, SWD, and SWL, global, dimensional, and segmental stroke work. The Journal of Thoracic and Cardiovascular Surgery 2000 120, 302-312DOI: (10.1067/mtc.2000.105828) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

Fig. 5 Relationship between unidimensional and global PRSW slopes (left panels) and x-axis intercepts (right panels) under control conditions and during pulmonary arterial constriction (PAC) or aortic constriction (AC). MwG, MwD, and MwL, Global, septal-free wall dimensional and free wall segmental PRSW slopes; Vw, Dw, and Lw, global, dimensional, and segmental PRSW x-axis intercepts. DW and LW were normalized to the steady-state end-diastolic dimensions under control conditions. The Journal of Thoracic and Cardiovascular Surgery 2000 120, 302-312DOI: (10.1067/mtc.2000.105828) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions