Reduced Intensity Conditioning Regimen Combined with Single Unit Cord Blood Transplantation Is Effective and Safe for Children with Inherited Metabolic.

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Presentation transcript:

Reduced Intensity Conditioning Regimen Combined with Single Unit Cord Blood Transplantation Is Effective and Safe for Children with Inherited Metabolic Disorders and Combined Immunodeficiency Diseases Mark Vander Lugt, MD, Xiaohua Chen, Ph.D, Randy Windreich, MD, Rakesh K. Goyal, MD, Elizabeth Stenger, MD, Maria Escolar, MD, Paul Szabolcs, MD Biology of Blood and Marrow Transplantation Volume 20, Issue 2, Pages S88-S89 (February 2014) DOI: 10.1016/j.bbmt.2013.12.112 Copyright © 2014 Terms and Conditions

Figure Panel A shows the median number and range of sjTREC copies/10^5 T cells plotted on the left Y-axis and shown using filled squares and solid lines. The median and range of TCR Vβ spectrotype complexity score (SCS) is plotted on the right Y-axis and shown using open circles and dashed lines. A normal SCS is equal to 184 (Wu CJ et al., Blood 2000). Panel B shows a representative TCR Vβ repertoire pre- and post-UCBT. Biology of Blood and Marrow Transplantation 2014 20, S88-S89DOI: (10.1016/j.bbmt.2013.12.112) Copyright © 2014 Terms and Conditions