Sudish C. Murthy, MD, PhD, Edward R. Nowicki, MD, MS, David P

Slides:

Advertisements

Similar presentations

Thomas W. Rice, MD, Deepak Khuntia, MD, Lisa A. Rybicki, MS, David J

Advertisements

Spinal cord protective strategies during descending and thoracoabdominal aortic aneurysm repair in the modern era: The role of intrathecal papaverine

Residual patient, anatomic, and surgical obstacles in treating active left-sided infective endocarditis Syed T. Hussain, MD, Nabin K. Shrestha, MD, Steven.

Robert J. Dabal, MD, James K

Surgical management of secondary tricuspid valve regurgitation: Annulus, commissure, or leaflet procedure? Jose L. Navia, MD, Edward R. Nowicki, MD,

Prognosis of patients removed from a transplant waiting list for medical improvement: Implications for organ allocation and transplantation for status.

Advising complex patients who require complex heart operations

Should lung transplantation be performed for patients on mechanical respiratory support? The US experience David P. Mason, MD, Lucy Thuita, MS, Edward.

It is not just about surgery versus stereotactic ablative radiotherapy, it is about curing as many patients with lung cancer as possible Alessandro Brunelli,

Siva Raja, MD, PhD, Thomas W. Rice, MD, John Ehrlinger, PhD, John R

Lars G. Svensson, MD, PhD, Lillian H. Batizy, MS, Eugene H

Effect of changes in postoperative spirometry on survival after lung transplantation David P. Mason, MD, Jeevanantham Rajeswaran, MSc, Liang Li, PhD,

Endovascular versus open elephant trunk completion for extensive aortic disease Eric E. Roselli, MD, Sreekumar Subramanian, MD, Zhiyuan Sun, BS, Jahanzaib.

The least of 3 evils: Exposure to red blood cell transfusion, anemia, or both? Gabriel Loor, MD, Jeevanantham Rajeswaran, PhD, Liang Li, PhD, Joseph F.

David P. Mason, MD, Jeevanantham Rajeswaran, MS, Sudish C

Surgical treatment of pseudoaneurysm of the thoracic aorta

Esophageal submucosa: The watershed for esophageal cancer

Duration of inotropic support after left ventricular assist device implantation: Risk factors and impact on outcome Soren Schenk, MD, Patrick M. McCarthy,

Reoperation After Mitral Valve Repair for Degenerative Disease

Centers for Disease Control “increased-risk” organ donor: Not so risky? Francis D. Pagani, MD, PhD The Journal of Thoracic and Cardiovascular Surgery

Sina Ercan, MD, Thomas W. Rice, MD, Sudish C. Murthy, MD, PhD, Lisa A

Coronary artery bypass grafting in diabetics: A growing health care cost crisis Sajjad Raza, MD, Joseph F. Sabik, MD, Ponnuthurai Ainkaran, MS, Eugene.

Effects of right ventricular morphology and function on outcomes of patients with degenerative mitral valve disease Ying Ye, BS, Ravi Desai, MD, Lina.

Albert S. Y. Chang, MD, Nicholas G. Smedira, MD, Catherine L

Too High for Transplantation

Multilevel data analysis: What? Why? How?

Should lung transplantation be performed using donation after cardiac death? The United States experience David P. Mason, MD, Lucy Thuita, MS, Joan M.

Spinal cord protective strategies during descending and thoracoabdominal aortic aneurysm repair in the modern era: The role of intrathecal papaverine

Does a similar procedure result in similar survival for women and men undergoing isolated coronary artery bypass grafting? Tamer Attia, MD, MSc, Colleen.

A. Marc Gillinov, MD, Eugene H. Blackstone, MD, Edward R

Capturing echocardiographic allograft valve function over time after allograft aortic valve or root replacement M. Mostafa Mokhles, PhD, MSc, Jeevanantham.

Risk-corrected impact of mechanical versus bioprosthetic valves on long-term mortality after aortic valve replacement Ole Lund, MD, PhD, Martin Bland,

Atrial fibrillation complicating lung cancer resection

A physiologic clinical study of achalasia: Should Dor fundoplication be added to Heller myotomy? Thomas W. Rice, MD, Alicia A. McKelvey, MD, Joel E.

Outcomes of less invasive J-incision approach to aortic valve surgery

Nicholas G. Smedira, MD, Katherine J. Hoercher, RN, Dustin Y

David P. Mason, MD, Lillian H. Batizy, MS, Jeffrey Wu, MD, Edward R

Aditya K. Kaza, MD The Journal of Thoracic and Cardiovascular Surgery

Value of accelerated multimodality therapy in stage IIIA and IIIB non–small cell lung cancer Malcolm M DeCamp, MD, Thomas W Rice, MD, David J Adelstein,

Comparative study of bronchial artery revascularization in lung transplantation Gösta B. Pettersson, MD, PhD, Karam Karam, MD, Lucy Thuita, MS, Douglas.

A first start for lung transplantation?

David P. Mason, MD, Dale H. Marsh, MD, Joan M. Alster, MS, Sudish C

Decision support in surgical management of ischemic cardiomyopathy

Third-time lung transplantation in a patient with cystic fibrosis

Impact of Anastomotic Airway Complications After Lung Transplantation

Lars G. Svensson, MD, PhD, Fernando A. Atik, MD, Delos M

Jeevanantham Rajeswaran, PhD, Eugene H. Blackstone, MD

Fenton H. McCarthy, MD, MS, Nimesh D. Desai, MD, PhD

Thomas W. Rice, MD, Deepak Khuntia, MD, Lisa A. Rybicki, MS, David J

Patient and Surgical Factors Influencing Air Leak After Lung Volume Reduction Surgery: Lessons Learned From the National Emphysema Treatment Trial Malcolm.

Colleen G. Koch, MD, MS, MBA, Edward R

Ventilatory dependency after cardiovascular surgery

Pathologic correlates of heparin-free donation after cardiac death in lung transplantation Chase R. Brown, BS, Alexis E. Shafii, MD, Carol F. Farver,

The use of mechanical circulatory support as a bridge to transplantation in pediatric patients: An analysis of the United Network for Organ Sharing database

Turki B. Albacker, MD, MSc, Eugene H. Blackstone, MD, Sarah J

David P. Mason, MD, Chase R. Brown, BS, Sudish C

How much does early fundoplication for lung transplant recipients with gastroesophageal reflux disease truly help? Challenges in escaping the perils of.

Mitral valve repair with aortic valve replacement is superior to double valve replacement A.Marc Gillinov, MD, Eugene H Blackstone, MD, Delos M Cosgrove,

Siva Raja, MD, PhD, Jay J. Idrees, MD, Eugene H

Jeffrey H. Shuhaiber, MD, Jeff Moore, MS, David B. Dyke, MD

The Journal of Thoracic and Cardiovascular Surgery

Discussion The Journal of Thoracic and Cardiovascular Surgery

Pulmonary hypertension is associated with worse early and late outcomes after aortic valve replacement: Implications for transcatheter aortic valve replacement

The future of cardiac surgery training: A survival guide

Reliability of risk algorithms in predicting early and late operative outcomes in high-risk patients undergoing aortic valve replacement Todd M. Dewey,

Pulmonary transplantation in Mounier-Kuhn syndrome: A case report

National trends in utilization and in-hospital outcomes of mechanical versus bioprosthetic aortic valve replacements Abby J. Isaacs, MS, Jeffrey Shuhaiber,

Identifying risk factors: Challenges of separating signal from noise

Lung Transplantation for Idiopathic Pulmonary Fibrosis

Fernando A. Atik, MD, Lars G. Svensson, MD, PhD, FACC, Eugene H

Presentation transcript:

Pretransplant gastroesophageal reflux compromises early outcomes after lung transplantation Sudish C. Murthy, MD, PhD, Edward R. Nowicki, MD, MS, David P. Mason, MD, Marie M. Budev, DO, MPH, Anthony I. Nunez, MD, Lucy Thuita, MS, Jeffrey T. Chapman, MD, Kenneth R. McCurry, MD, Gösta B. Pettersson, MD, PhD, Eugene H. Blackstone, MD The Journal of Thoracic and Cardiovascular Surgery Volume 142, Issue 1, Pages 47-52.e3 (July 2011) DOI: 10.1016/j.jtcvs.2011.04.028 Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Estimated mean forced 1-second expiratory volume (FEV1) expressed as a percent of predicted, stratified by presence or absence of gastroesophageal reflux disease (GERD). Symbols represent crude depictions of raw data unadjusted for repeated measures. Dashed lines represent 68% confidence limits for the mean. The Journal of Thoracic and Cardiovascular Surgery 2011 142, 47-52.e3DOI: (10.1016/j.jtcvs.2011.04.028) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Estimated mean forced 1-second expiratory volume (FEV1) after lung transplantation according to double versus single lung transplant and presence or absence of gastroesophageal reflux disease (GERD). The Journal of Thoracic and Cardiovascular Surgery 2011 142, 47-52.e3DOI: (10.1016/j.jtcvs.2011.04.028) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Survival after lung transplantation according to presence or absence of gastroesophageal reflux disease (GERD). Each symbol represents a death, vertical bars confidence limits equivalent to ±1 standard error, and numbers in parentheses patients remaining at risk. The Journal of Thoracic and Cardiovascular Surgery 2011 142, 47-52.e3DOI: (10.1016/j.jtcvs.2011.04.028) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 Proportion of patients in vascular rejection grade 0 after lung transplantation according to presence or absence of gastroesophageal reflux disease (GERD). The format is as in Figure 1, except confidence bands have been suppressed for clarity. The Journal of Thoracic and Cardiovascular Surgery 2011 142, 47-52.e3DOI: (10.1016/j.jtcvs.2011.04.028) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure E1 Number of patients with forced 1-second expiratory volume (FEV1) measurements available at and beyond various time points, and number of FEV1 measurements available for analysis. A, Patients with gastroesophageal reflux disease. B, Patients without gastroesophageal reflux disease. The Journal of Thoracic and Cardiovascular Surgery 2011 142, 47-52.e3DOI: (10.1016/j.jtcvs.2011.04.028) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure E2 Number of patients with biopsy tissue available at and beyond various time points, and number of biopsy results available for analysis. Also shown is percentage of evaluable patients with biopsies. A, Patients with gastroesophageal reflux disease. B, Patients without gastroesophageal reflux disease. The Journal of Thoracic and Cardiovascular Surgery 2011 142, 47-52.e3DOI: (10.1016/j.jtcvs.2011.04.028) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure E3 Survival after lung transplantation according to pH test availability. Format is as in Figure 4. The Journal of Thoracic and Cardiovascular Surgery 2011 142, 47-52.e3DOI: (10.1016/j.jtcvs.2011.04.028) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions