Sending Cancer into the Fetal Position Hannah A. Pizzato, Deepta Bhattacharya  Cell Stem Cell  Volume 22, Issue 4, Pages 479-480 (April 2018) DOI: 10.1016/j.stem.2018.03.007 Copyright © 2018 Elsevier Inc. Terms and Conditions

Figure 1 iPSC Vaccination Promotes a Robust T Cell Response Leading to Tumor Immunity Mice were vaccinated with either saline (A) or an iPSC and CpG cocktail (B). Vaccinated mice were then injected with breast, skin, or lung cancer cells. Tumors (blue circles) of control mice grew, but those of mice vaccinated with iPSCs did not. The iPSC-vaccinated mice possessed activated T cells reactive to epitopes shared between iPSCs and cancer cells (orange triangles). Upon adoptive transfer of these T cells to a mouse already bearing a tumor, the tumor regressed in response to T cells from iPSC-vaccinated mice but did not do so in response to cells from control mice. Cell Stem Cell 2018 22, 479-480DOI: (10.1016/j.stem.2018.03.007) Copyright © 2018 Elsevier Inc. Terms and Conditions