PCR cycle threshold value predicts the course of Clostridium difficile infection N. Jazmati, M. Hellmich, B. Ličanin, G. Plum, A.J. Kaasch Clinical Microbiology and Infection Volume 22, Issue 2, Pages e7-e8 (February 2016) DOI: 10.1016/j.cmi.2015.09.012 Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions
Fig. 1 (a) Comparison of the Clostridium difficile PCR cycle thresholds of stool samples from patients in the different clinical groups. The horizontal line in each box indicates the median; whereas the top and bottom lines represent the 75th and 25th centiles, respectively. The ‘whiskers’ extend to the minimum and maximum value per group. *Cycle threshold (CT) values of patients with severe disease were significantly lower compared with patients of the other four groups (p 0.02). (CDI, Clostridium difficile infection; TC, toxigenic culture). (b) The area under the receiver operating characteristic (ROC) curve for toxin B cycle threshold as a predictor for severe disease was significantly increased (area under ROC curve: 0.77 (95% CI 0.62–0.92, p 0.013). Clinical Microbiology and Infection 2016 22, e7-e8DOI: (10.1016/j.cmi.2015.09.012) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions